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Milbemycin oxime
go.drugbank.com/drugs/DB11531ExperimentalVet approvedMixtures: Nexgard Spectra 150mg/30mg Chewable Tablets for Dogs >30-60kg, Nexgard Spectra 9mg/2mg Chewable Tablets for Dogs 2-3.5kgThymidine
go.drugbank.com/drugs/DB04485ApprovedInvestigational[A274683, A274688] As of now, its primary role is in research and as a sensitizer or modulator in experimental chemotherapy regimens, rather than a standalone, approved therapeutic agent. … Thymidine is a naturally occurring deoxyribonucleoside that is a crucial component of the DNA salvage pathway and a building block for DNA synthesis.
Categories: Nucleic Acids, Nucleotides, and NucleosidesTrypsin
go.drugbank.com/drugs/DB11237ApprovedInvestigationalVet approvedTrypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. … This nucleophilic attack is facilitated by the catalytic triad consisting of histidine-57, aspartate-102, and serine-195.
Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansStabilin-1
go.drugbank.com/bio_entities/BE0010944TargetHumansBinds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. … When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis.
Synonyms: Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1Ethynodiol diacetate
go.drugbank.com/drugs/DB00823ApprovedA synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. … Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug
Mixtures: Ethynodiol Diacetate and Ethinyl Estradiol, Ethynodiol Diacetate and Ethinyl EstradiolCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemElotuzumab
go.drugbank.com/drugs/DB06317ApprovedInvestigationalFood and Drug Administration. Elotuzumab is marketed under the brand Empliciti™ by Bristol-Myers Squibb. … Elotuzumab is produced in NS0 cells by recombinant DNA technology. Elotuzumab has a theoretical mass of 148.1 kDa for the intact antibody. Elotuzumab was approved on November 30, 2015 by the U.S.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsLubiprostone
go.drugbank.com/drugs/DB01046ApprovedInvestigationalLubiprostone is a medication used in the management of idiopathic chronic constipation. … Activation of these channels promotes the secretion of a chloride-rich fluid that soften the stool, increase gastrointestinal motility, and induce spontaneous bowel movements (SBM).
Categories: Alimentary Tract and MetabolismOprelvekin
go.drugbank.com/drugs/DB00038ApprovedInvestigationalWithdrawnHowever, it displays comparable biological activity compared to the natural IL-11 _in vitro_ and _in vivo_. Oprelvekin works by stimulating megakaryocytopoiesis and thrombopoiesis. … Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: IL-11Dipivefrin
go.drugbank.com/drugs/DB00449ApprovedWithdrawnDipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Categories: Antiglaucoma Preparations and Miotics, Sympathomimetics in Glaucoma Therapy