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Displaying results 31 - 40 of 11587 in total
  1. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … across various SCLC disease stages and treatment statuses.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  2. Drug

    SP1049C

    go.drugbank.com/drugs/DB04978
    Experimental

    Median survival is encouraging and correlates strongly with dose levels.[A260416] … SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic block copolymers.

    Synonyms: doxorubicin with pluronics F-127 and L-61, Doxorubicin HCl with pluronic L-61 and pluronic F-127
  3. Drug

    Pyrethrum extract

    go.drugbank.com/drugs/DB11087
    Approved

    Pyrethrum extract is also used used to treat head, body, and pubic lice infections. … The active compound is absorbed by the lice and destroys them by acting on their nervous systems but is thought to exert minimal effect on humans.

    Mixtures: Lice-Nil Lice and Eggs Killer, Medi and Lice Lice KillingSynonyms: Pyrethrins and pyrethroids
  4. Drug

    PlasmaCord

    go.drugbank.com/drugs/DB16363
    Experimental

    PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. … [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).

    Synonyms: Human umbilical cord and placental blood plasma
  5. Drug

    VA-MENGOC-BC®

    go.drugbank.com/drugs/DB15800
    Experimental

    VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. … The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C.

    Synonyms: Meningococcal polysaccharide vaccine groups B and C
  6. Drug

    Probenecid

    go.drugbank.com/drugs/DB01032
    ApprovedInvestigational

    It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. … Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.

    Mixtures: Probenecid and Colchicine, Probenecid and ColchicineCategories: colchicine and probenecid, Genito Urinary System and Sex Hormones
  7. Drug

    renizgamglogene autogedtemcel

    go.drugbank.com/drugs/DB25530
    Investigational

    renizgamglogene autogedtemcel is a biologic drug. renizgamglogene autogedtemcel is under investigation in clinical trial NCT05444894 (EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Depe...

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 promoters, autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP) at the HBG1 and HBG2 promoters
  8. Drug

    Benzoylpas

    go.drugbank.com/drugs/DB19382
    ApprovedWithdrawn

    Synonyms: Benzoic acid, 4-(benzoylamino)-2-hydroxy-
  9. Drug

    AFM-13

    go.drugbank.com/drugs/DB17404
    Investigational

    Synonyms: Recombinant antibody construct against human CD30 and CD16A
  10. Drug

    Hepatitis b virus s protein, pre-s1 protein and pre-s2 protein virus like particles

    go.drugbank.com/drugs/DB33825
    Experimental

    Synonyms: Hepatitis b virus s protein, pre-s1 protein and pre-s2 protein virus like particles