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Displaying results 31 - 40 of 144494 in total
  1. Drug

    Apadamtase alfa

    go.drugbank.com/drugs/DB15164
    ApprovedInvestigational

    Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency in ADAMTS13 is responsible for the microangiopathic complications associated with cTTP

    Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansSynonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs
  2. Drug

    Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein

    go.drugbank.com/drugs/DB33819
    Experimental

    Synonyms: Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein
  3. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    [L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045] … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.

    Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAIN, SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION.
  4. Drug

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

    go.drugbank.com/drugs/DB18681
    Experimental

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. … It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
  5. Drug

    Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)

    go.drugbank.com/drugs/DB02182
    Experimental

    Synonyms: Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)
  6. Drug

    Gibberella fujikuroi

    go.drugbank.com/drugs/DB15511
    Approved

    Gibberella fujikuroi allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, fusarium moniliforme
  7. Drug

    Human Embryonic Stem Cell-derived M Cell

    go.drugbank.com/drugs/DB15734
    Investigational

    and fibrosis. … However, the difference comes with IMRCs displaying a higher quality of consistency, having stronger immunomodulatory and anti-fibrotic functions, and being stronger in potential treatment of lung injury

    Synonyms: immunity- and matrix-regulatory cells, Immunity-and-matrix-regulatory cells
  8. Drug

    ALX-009

    go.drugbank.com/drugs/DB17916
    Investigational

    Synonyms: Hypothiocyanite and lactoferrin
  9. Drug

    Glyceryl monostearate

    go.drugbank.com/drugs/DB11250
    Approved

    It is commonly used as an emulsifier in foods.

    Synonyms: Geleol mono and diglycerides
  10. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … across various SCLC disease stages and treatment statuses.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific