Glyceryl monostearate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Glyceryl monostearate
DrugBank Accession Number
DB11250
Background

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 358.5558
Monoisotopic: 358.308309832
Chemical Formula
C21H42O4
Synonyms
  • Geleol mono and diglycerides
  • Glycerin monostearate
  • Glycerol monostearate
  • Glyceroli monostearas
  • Glyceryl monooctadecanoate
  • Glyceryl monopalmitostearate
  • Glyceryl stearate
  • Monoglyceryl stearate
  • Monostearate (glyceride)
  • Monostearin
  • Stearic acid, monoester with glycerol
  • Stearoylglycerol

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Banacos Cica MaskGlyceryl monostearate (0.416 g/100g) + Allantoin (0.01 g/100g) + Ethanol (0.01 mL/100g)PatchTopicalCleoslab Co.,Ltd2020-07-16Not applicableUS flag
Cho-A Care Lot 1%Glyceryl monostearate (10 mg/50g) + Hydrocortisone (10 mg/50g)LotionTopicalCho-A Pharm.Co.,Ltd.2019-10-25Not applicableUS flag
Fresh Med SolutionGlyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL)LiquidTopicalATOMY CO LTD2011-06-242011-06-24US flag
Fresh Med SolutionGlyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL) + Glycerin (1.744 mL/40mL)LiquidTopicalATOMY CO LTD2011-07-012011-07-01US flag
Fresh Med SolutionGlyceryl monostearate (0.4 g/40mL) + Ethanol (1.6 g/40mL) + Glycerin (1.744 g/40mL)LiquidTopicalAtomy Co., Ltd.2011-07-182017-12-01US flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Fresh Med SolutionGlyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL)LiquidTopicalATOMY CO LTD2011-06-242011-06-24US flag
Mycellcare All in One SerumGlyceryl monostearate (0.728 g/100mL) + Allantoin (0.145 g/100mL) + Glycerin (4.16 g/100mL) + Nicotinamide (2.8 g/100mL)LiquidTopicalPHARMACAL-INTERNATIONAL. CO., LTD2017-08-16Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
258491E1RZ
CAS number
31566-31-1
InChI Key
VBICKXHEKHSIBG-UHFFFAOYSA-N
InChI
InChI=1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
IUPAC Name
2,3-dihydroxypropyl octadecanoate
SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

References

General References
Not Available
Human Metabolome Database
HMDB0031075
ChemSpider
23095
RxNav
1311155
ChEBI
75555
ChEMBL
CHEMBL255696
Wikipedia
Glycerol_monostearate

Clinical Trials

Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package
PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
PatchTopical
LotionTopical
LiquidTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00108 mg/mLALOGPS
logP6.73ALOGPS
logP5.97Chemaxon
logS-5.5ALOGPS
pKa (Strongest Acidic)13.62Chemaxon
pKa (Strongest Basic)-3Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area66.76 Å2Chemaxon
Rotatable Bond Count20Chemaxon
Refractivity103.31 m3·mol-1Chemaxon
Polarizability46.63 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability0Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
GC-MS Spectrum - EI-BGC-MSsplash10-007k-9530000000-e7c8759540fb484bf4af
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-0f6t-2910000000-94597a6f353acb356316
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0596-3049000000-f2db4bb2b80b913984b8
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-066u-9074000000-b8fbf10e064e48310116
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-06e9-9070000000-38335f4f1039c8ea1472
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-00g3-9385000000-3b3559d0849687184856
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-053u-9580000000-55fbdec35255781e7d90
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-052f-9200000000-f30749edd12bf5eb2a23
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-231.3163824
predicted
DarkChem Lite v0.1.0
[M-H]-188.87633
predicted
DeepCCS 1.0 (2019)
[M+H]+232.2132824
predicted
DarkChem Lite v0.1.0
[M+H]+191.42664
predicted
DeepCCS 1.0 (2019)
[M+Na]+229.4525824
predicted
DarkChem Lite v0.1.0
[M+Na]+198.49011
predicted
DeepCCS 1.0 (2019)

Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53