Glyceryl monostearate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Glyceryl monostearate
Accession Number
DB11250
Description

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 358.5558
Monoisotopic: 358.308309832
Chemical Formula
C21H42O4
Synonyms
  • Geleol mono and diglycerides
  • Glycerin monostearate
  • Glycerol monostearate
  • Glyceroli monostearas
  • Glyceryl monooctadecanoate
  • Glyceryl monopalmitostearate
  • Glyceryl stearate
  • Monoglyceryl stearate
  • Monostearate (glyceride)
  • Monostearin
  • Stearic acid, monoester with glycerol
  • Stearoylglycerol

Pharmacology

Pharmacology
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Indication
Not Available
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Medicalerrors
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products
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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Banacos Cica MaskGlyceryl monostearate (0.416 g/100g) + Allantoin (0.01 g/100g) + Ethanol (0.01 mL/100g)PatchTopicalCleoslab Co.,Ltd2020-07-16Not applicableUS flag
Cho-A Care Lot 1%Glyceryl monostearate (10 mg/50g) + Hydrocortisone (10 mg/50g)LotionTopicalCho-A Pharm.Co.,Ltd.2019-10-25Not applicableUS flag
Fresh Med SolutionGlyceryl monostearate (0.4 g/40mL) + Ethanol (1.6 g/40mL) + Glycerin (1.744 g/40mL)LiquidTopicalAtomy Co., Ltd.2011-07-182017-12-01US flag
Fresh Med SolutionGlyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL) + Glycerin (1.744 mL/40mL)LiquidTopicalATOMY CO LTD2011-07-012011-07-01US flag
Fresh Med SolutionGlyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL)LiquidTopicalATOMY CO LTD2011-06-242011-06-24US flag
Mycellcare All in One SerumGlyceryl monostearate (0.728 g/100mL) + Allantoin (0.145 g/100mL) + Glycerin (4.16 g/100mL) + Nicotinamide (2.8 g/100mL)LiquidTopicalPHARMACAL-INTERNATIONAL. CO., LTD2017-08-16Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Fresh Med SolutionGlyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL)LiquidTopicalATOMY CO LTD2011-06-242011-06-24US flag
Mycellcare All in One SerumGlyceryl monostearate (0.728 g/100mL) + Allantoin (0.145 g/100mL) + Glycerin (4.16 g/100mL) + Nicotinamide (2.8 g/100mL)LiquidTopicalPHARMACAL-INTERNATIONAL. CO., LTD2017-08-16Not applicableUS flag

Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
258491E1RZ
CAS number
31566-31-1
InChI Key
VBICKXHEKHSIBG-UHFFFAOYSA-N
InChI
InChI=1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
IUPAC Name
2,3-dihydroxypropyl octadecanoate
SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

References

General References
Not Available
Human Metabolome Database
HMDB0031075
ChemSpider
23095
RxNav
1311155
ChEBI
75555
ChEMBL
CHEMBL255696
Wikipedia
Glycerol_monostearate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2RecruitingTreatmentCarcinoma, Breast1
1RecruitingTreatmentSkin and Subcutaneous Tissue Disorders1
Not AvailableCompletedTreatmentHyperpigmentation / Rhytides / Solar Elastosis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
PatchTopical
LotionTopical
LiquidTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00108 mg/mLALOGPS
logP6.73ALOGPS
logP5.97ChemAxon
logS-5.5ALOGPS
pKa (Strongest Acidic)13.62ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area66.76 Å2ChemAxon
Rotatable Bond Count20ChemAxon
Refractivity103.31 m3·mol-1ChemAxon
Polarizability46.63 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability0ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
GC-MS Spectrum - EI-BGC-MSsplash10-007k-9530000000-e7c8759540fb484bf4af
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-0f6t-2910000000-94597a6f353acb356316
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a6r-6059000000-d28aa7b6b0e905156c3c
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-004i-9142000000-045b6aa1714a613c5bb7
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-004i-9360000000-2aed6b4466659b889e1d
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0api-2095000000-c7d2a97c938011bb80b1
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-00lr-4091000000-2328f45eed978a1a2d52
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0aou-9060000000-a1846373cdc4ed9076b5

Drug created on December 03, 2015 16:51 / Updated on June 12, 2020 16:53