Search

Displaying results 31 - 40 of 144705 in total
  1. Drug

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

    go.drugbank.com/drugs/DB18681
    Experimental

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. … It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
  2. Drug

    Exagamglogene autotemcel

    go.drugbank.com/drugs/DB15572
    ApprovedInvestigational

    [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS. … Exagamglogene autotemcel is an autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor cells which has been investigated in clinical trials for the treatment of severe SCD and severe

    Categories: Blood and Blood Forming OrgansSynonyms: Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated
  3. Drug

    Silk sericin

    go.drugbank.com/drugs/DB15531
    Investigational

    Synonyms: Sericin (from silkworm)Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    Gibberella fujikuroi

    go.drugbank.com/drugs/DB15511
    Approved

    Gibberella fujikuroi allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, fusarium moniliforme
  5. Drug

    Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)

    go.drugbank.com/drugs/DB02182
    Experimental

    Synonyms: Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)
  6. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … across various SCLC disease stages and treatment statuses.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  7. Drug

    Human Embryonic Stem Cell-derived M Cell

    go.drugbank.com/drugs/DB15734
    Investigational

    These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. … and fibrosis.

    Synonyms: immunity- and matrix-regulatory cells, Immunity-and-matrix-regulatory cells
  8. Drug

    ALX-009

    go.drugbank.com/drugs/DB17916
    Investigational

    Synonyms: Hypothiocyanite and lactoferrin
  9. Drug

    Taniraleucel

    go.drugbank.com/drugs/DB18311
    Investigational

    Synonyms: Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells., The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell
  10. Drug

    Glyceryl monostearate

    go.drugbank.com/drugs/DB11250
    Approved

    It is commonly used as an emulsifier in foods.

    Synonyms: Geleol mono and diglycerides