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Nipocalimab
go.drugbank.com/drugs/DB16257ApprovedInvestigationalNipocalimab-aahu is a neonatal Fc receptor (FcRn) blocker used to treat certain antibody-mediated autoimmune diseases. … [L64042] It is an aglycosylated, fully human IgG1 monoclonal antibody that binds FcRn and blocks the receptor's recycling of immunoglobulin G (IgG), thereby lowering circulating IgG levels, including pathogenic
Categories: Neonatal Fc Receptor BlockerSynonyms: immunoglobulin G1-lambda, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], Homo sapiens monoclonal, Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimerBenzoyl peroxide
go.drugbank.com/drugs/DB09096ApprovedInvestigational[A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover of epithelial cells. … Benzoyl peroxide is a commonly used drug in topical treatments for acne.
Mixtures: 3 Step Acne System Well at Walgreens, 3 Step Acne System Well at WalgreensProducts: BENZAC AC 5, POLYBENZA AQ 5Beclomethasone dipropionate
go.drugbank.com/drugs/DB00394ApprovedInvestigational[L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which acts on the glucocorticoid receptor to mediates its therapeutic action. … Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and later in a dry powder inhaler and an aqueous nasal spray.
Categories: Corticosteroid Hormone Receptor AgonistsInternational brands: Clenil-AAluminum sulfate
go.drugbank.com/drugs/DB11239ApprovedMedically, it is primarily used as a coagulating agent in minor cuts and abrasions as well as deodorant [L2144]. … Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table [L2148].
Products: Sil Trax As No 8, Sil Trax As No 10Cromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalA chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Products: CROMO AT 1A PHARMA, CROMOGLICATO DE SODIO AL 2%Loperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Products: A D, Imodium ADClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedAs well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. … well as athlete's foot [A174097].
Mixtures: SAEROGENTA-A CREAMProducts: Au Kah Chuen Antifungal, Mycozyl ACTagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigationalTagraxofusp is a CD123-directed cytotoxin. … a myeloid malignancy in the dendritic cell lineage.
Synonyms: Diphtheria toxin-il-3 fusion protein targeting IL-3 receptorLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Products: LEFLUNOMID AL 10MG FILMTAB, LEFLUNOMID AL 20MG FILMTAB