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Displaying results 31 - 40 of 9220 in total
  1. Drug

    Timolumab

    go.drugbank.com/drugs/DB18597
    Investigational

    Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).

    Synonyms: recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1)
  2. Drug

    TOL-101

    go.drugbank.com/drugs/DB16980
    Investigational

    Synonyms: Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor, TOL 101
  3. Drug

    BS-001

    go.drugbank.com/drugs/DB17415
    Investigational

    BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human use (rHSV2hGM-CSF).

    Synonyms: Recombinant Oncolytic Herpes Simplex Virus Type II (OH2) Therapeutic Injection (Vero Cell) for Human Use
  4. Drug

    Trastuzumab botidotin

    go.drugbank.com/drugs/DB17413
    Experimental

    A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable

    Synonyms: Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5
  5. Drug

    AGIL-FA

    go.drugbank.com/drugs/DB16973
    Experimental

    Synonyms: Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein
  6. Drug

    AVR-RD-04

    go.drugbank.com/drugs/DB18644
    Experimental

    AVR-RD-04 is an investigational gene therapy for cystinosis. … It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.

    Synonyms: autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin
  7. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin … [A257709] Although its detailed molecular mechanisms have yet to be understood, doxorubicin is generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and

    Synonyms: MTC-DOX for InjectionProducts: DOXABIN POWDER FOR SOLUTION FOR INJECTION 10MG/VIAL, DOXABIN POWDER FOR SOLUTION FOR INJECTION 50MG/VIAL
  8. Drug

    ETX101

    go.drugbank.com/drugs/DB18579
    Investigational

    ETX101 is a non-replicating recombinant adeno associated viral vector, serotype 9, designed to promote increased transcription of SCN1A gene.

    Synonyms: non-replicating recombinant adeno associated viral vector, serotype 9, designed to promote increased transcription of SCN1A gene
  9. Drug

    Dasiprotimut-T

    go.drugbank.com/drugs/DB17287
    Experimental

    Dasiprotimut-T is a personalized therapeutic vaccine against B-cell lymphomas.[A254701] It has been investigated in clinical trials.

    Categories: dasiprotimut-TSynonyms: Autologous lymphoma-derived immunoglobulin idiotype antigen vaccine conjugated to keyhole limpet hemocyanin, Dasiprotimut-T
  10. Drug

    KRN-330

    go.drugbank.com/drugs/DB19075
    Investigational

    Anti-a33 fully-human monoclonal antibody is under investigation in clinical trial NCT00838578 (Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer).

    Synonyms: HUMAN MONOCLONAL ANTIBODY TO COLON CANCER ANTIGEN A33