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Displaying results 391 - 400 of 10000 in total
  1. Drug

    Streptolydigin

    go.drugbank.com/drugs/DB04785
    Experimental

    Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.

    Synonyms: Afragilimycin A
  2. Drug

    Loncastuximab tesirine

    go.drugbank.com/drugs/DB16222
    ApprovedInvestigational

    Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. … [L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial.

    Synonyms: Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine linkerCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    Hexanoyl-CoA

    go.drugbank.com/drugs/DB02563
    Experimental

    Synonyms: n-hexanoyl-coenzyme A, S-Hexanoyl-coenzym-ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  4. Drug

    Kanamycin

    go.drugbank.com/drugs/DB01172
    ApprovedInvestigationalVet approvedWithdrawn

    Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.

    Synonyms: Kanamycin A, 4,6-diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-α-D-glucosideInternational brands: Kancin-L
  5. Drug

    5-Mercaptoethanol-2-decenoyl-coenzyme A

    go.drugbank.com/drugs/DB03698
    Experimental

    Synonyms: 5-Mercaptoethanol-2-decenoyl-coenzyme A
  6. Drug

    Viagenpumatucel-L

    go.drugbank.com/drugs/DB16348
    Investigational

    Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).

    Synonyms: Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine, Viagenpumatucel l
  7. Drug

    Acetoacetyl-CoA

    go.drugbank.com/drugs/DB03059
    Experimental

    Synonyms: S-Acetoacetyl-coenzym A, S-acetoacetyl-coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  8. Drug

    Echinomycin

    go.drugbank.com/drugs/DB15582
    Experimental

    Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from _Streptomyces echinatus_ that binds to DNA and inhibits RNA synthesis.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Quinomycin A
  9. Drug

    Lixadesiran

    go.drugbank.com/drugs/DB17295
    Experimental

    Synonyms: Rna, (a-c-a-u-c-a-u-c-a-g-a-c-c-a-g-g-c-a-c-c-a-g-a-c-c), complex with rna (g-g-u-c-u-g-g-u-g-c-c-u-g-g-u-c-u-g-a-u-g-a-u-g-u) (1:1)
  10. Drug

    Pepstatin

    go.drugbank.com/drugs/DB21282
    Experimental

    Pepstatin is a small molecule drug. Pepstatin has a monoisotopic molecular weight of 685.46 Da.

    Synonyms: Pepstatin a