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Xaluritamig
go.drugbank.com/drugs/DB18137InvestigationalXaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Synonyms: immunoglobulin G1-scFv-CH/G1-kappa, anti-[Homo sapiens STEAP1 (STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecificOrciprenaline
go.drugbank.com/drugs/DB00816ApprovedA beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Products: Alupent Syr 10mg/5.0ml, Alupent Liq 50mg/mlProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedA low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy.
Mixtures: Estradiol and ProgesteroneCategories: progesterone and estrogen, Progesterone and DerivativesEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalEsomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme … It can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including [DB01060], [DB01211], and [DB00916], for example.
Mixtures: VIMOVO 500MG/20MG MODIFIED-RELEASE TABLETS, Naproxen and esomeprazole magnesiumCategories: Alimentary Tract and Metabolism, Omeprazole and enantiomerMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigational[A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval in the US in 1995.[L12207] … It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels.
Mixtures: XIGDUO®XR 5MG/1000MG, Tablet 50mg/1000mgCategories: Drugs Used in Diabetes, metformin and acarboseRitodrine
go.drugbank.com/drugs/DB00867ApprovedWithdrawnAdrenergic beta-agonist used to control premature labor.
Categories: Genito Urinary System and Sex HormonesProducts: Yutopar Tab 10mg, Yutopar Inj 50mg/5mlCloxacillin
go.drugbank.com/drugs/DB01147ApprovedInvestigationalVet approvedA semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].
International brands: Auropen Inj., Apo-CloxiProducts: Apo Cloxi Cap 500mg, Apo Cloxi Cap 250mgTrifluoperazine
go.drugbank.com/drugs/DB00831ApprovedIt is used as an antipsychotic and an antiemetic.
Products: Stelazine Tab 10mg, Novo-trifluzine - Tab 10mgMaprotiline
go.drugbank.com/drugs/DB00934ApprovedIt differs from TCAs in that it does not appear to block serotonin reuptake. … Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder.
Categories: Tricyclics and Other Norepinephrine-reuptake InhibitorsProducts: Ludiomil Tab 10mg, Novo-maprotiline - Tab 10mgBeclomethasone dipropionate
go.drugbank.com/drugs/DB00394ApprovedInvestigationalBeclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and later in a dry powder inhaler and an aqueous nasal spray. … [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which acts on the glucocorticoid receptor to mediates its therapeutic action.
Mixtures: Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation, INDAFLEX-IBCategories: Alimentary Tract and Metabolism, formoterol and beclometasone