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Buprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approved[A186215,A186218] It also means that opioid-dependent patients do not experience sedation or euphoria at the same rate that they might experience with more potent opioids, improving quality of life for … [A186286] For example, buprenorphine dissociates from opioid receptors very slowly, resulting in a long duration of action and relief from pain or withdrawal symptoms for upwards of 24-36 hours.
Categories: Heterocyclic Compounds with 4 or More RingsProducts: TRANSTEC 35 UG, TRANSTEC 70 UGCoenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Categories: Detoxifying Agents for Antineoplastic Treatment, Compounds used in a research, industrial, or household settingProducts: Mesna for Injection, CONCENTRATE SOLUTION FOR INJECTION 400MG/4MLAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigational[A237054] Anifrolumab has also been investigated for the treatment of Scleroderma.[A237044] Anifrolumab was granted FDA approval on 30 July 2021.[L34929] … [A237074,L34929] The standard therapy for systemic lupus erythematosus consists of antimalarials like [hydroxychloroquine], glucocorticoids like [dexamethasone], and disease modifying antirheumatic drugs
Products: SAPHNELO 300MG CONCENTRATE FOR SOLUTION FOR INFUSIONGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalIt was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers.
Products: GEMZAR 1gm POWDER FOR SOLUTION FOR INFUSION, GEMZAR 200mg Powder for Solution for InfusionEfmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalIt is commonly marketed as Elocta or Eloctate for intravenous injection. … It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It is suitable for all age groups.
Products: ELOCTATE® 250 UI, ELOCTATE® 500 UIClofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalIt is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Products: EVOLTRA 1 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION, NUCLOFAR Clofarabine 1mg/mL Concentrate for Solution for InfusionRemdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigational[A222398] Remdesivir (GS-5734) is an adenosine triphosphate analogue first described in the literature in 2016 as a potential treatment for Ebola. … [L39640] Remdesivir in combination with [baricitinib] for the treatment of COVID-19, was granted an FDA Emergency Use Authorization on November 19, 2020.[L22619]
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL), VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIALNecitumumab
go.drugbank.com/drugs/DB09559ApprovedInvestigationalWithdrawnNecitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC).
Products: PORTRAZZA CONCENTRATE FOR SOLUTION FOR INFUSION 800MG/50MLIdarucizumab
go.drugbank.com/drugs/DB09264ApprovedApproved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of dabigatran-associated bleeding in life-threatening or surgically induced situations. … anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney disease, concomitant NSAID or
Products: PRAXBIND Solution for Injection/Infusion 50 mg/ml, PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/MLAmphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalAmphotericin B shows a high order of in vitro activity against many species of fungi.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: AMPHOTRET FOR INJECTION USP 50MG, Amphotericin B for Injection, USP