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Displaying results 3991 - 4000 of 6074 in total
  1. Drug

    Nisoldipine

    go.drugbank.com/drugs/DB00401
    Approved

    Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in s...

    Categories: Antihypertensive Agents Indicated for Hypertension
  2. Drug

    Metolazone

    go.drugbank.com/drugs/DB00524
    ApprovedInvestigational

    A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.

    Categories: Antihypertensive Agents Indicated for Hypertension
  3. Drug

    SUVN-502

    go.drugbank.com/drugs/DB06140
    Investigational

    SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimer

  4. Drug

    Eberconazole

    go.drugbank.com/drugs/DB13656
    Investigational

    Eberconazole is a broad-spectrum imidazole derivative.

    Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
  5. Drug

    Vosilasarm

    go.drugbank.com/drugs/DB13939
    Investigational

    RAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.

  6. Drug

    ISIS 104838

    go.drugbank.com/drugs/DB16201
    Investigational

    ISIS 104838 is under investigation in clinical trial NCT00048321 (ISIS 104838, an Inhibitor of Tumor Necrosis Factor, for Active Rheumatoid Arthritis).

  7. Drug

    Dalcinonacog alfa

    go.drugbank.com/drugs/DB17707
    Investigational

    It is being investigated for the treatment of hemophilia B.[A259058]

  8. Drug

    GT-AS

    go.drugbank.com/drugs/DB17883
    Experimental

    GT-AS recombinant adeno-associated virus serotype 9 vector containing the transgene UBE3A encoding for ubiquitin protein ligase E3A/E6-AP.

  9. Drug

    OTOF-GT

    go.drugbank.com/drugs/DB18129
    Investigational

    OTOF-GT is a dual vector AAV gene therapy being investigated for the restoration of hearing loss associated with otoferlin deficiency.

  10. Drug

    TTX-MC138

    go.drugbank.com/drugs/DB18628
    Investigational

    [L48335] It is under investigation for the treatment of various metastatic cancers.