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Selisistat
go.drugbank.com/drugs/DB13978InvestigationalSelective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3
GC-373
go.drugbank.com/drugs/DB15797ExperimentalThe results showed potent inhibition of the target, suggesting that GC-373 holds therapeutic potential for Covid-19[A219036].
Categories: Experimental Unapproved Treatments for COVID-19C326
go.drugbank.com/drugs/DB06017ExperimentalC326 is an investigational compound under investigation in clinical trial NCT00353756 (Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease) for the treatment
Me-4(18F)DG
go.drugbank.com/drugs/DB19207InvestigationalMe-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).
ASP-3026
go.drugbank.com/drugs/DB12729InvestigationalASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein
Alisertib
go.drugbank.com/drugs/DB05220InvestigationalAlisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms of cancer.
Bicifadine
go.drugbank.com/drugs/DB04889InvestigationalBicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain.
Acetophenazine
go.drugbank.com/drugs/DB01063ApprovedIt is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.
Amodiaquine
go.drugbank.com/drugs/DB00613ApprovedInvestigationalA 4-aminoquinoquinoline compound with anti-inflammatory properties.