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Thioproperazine
go.drugbank.com/drugs/DB01622ApprovedThioproperazine is a potent neuroleptic with antipsychotic properties. … It is virtually without antiserotonin and hypotensive action and has no antihistaminic property.
Categories: Heterocyclic Compounds, 3-Ring, Adrenergic alpha-1 Receptor AntagonistsSynonyms: N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide, N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamideImazodan
go.drugbank.com/drugs/DB20144ExperimentalImazodan is a small molecule drug. The usage of the INN stem '-dan' in the name indicates that Imazodan is a cardiac stimulant, pimobendan derivative. … Imazodan has a monoisotopic molecular weight of 240.1 Da.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingMPI-674
go.drugbank.com/drugs/DB05749ExperimentalAIs are a class of drugs that reduce the amount of estrogen circulating in the body by binding to and inhibiting the enzyme aromatase, which is responsible for converting certain hormones to estrogen. … MPI-674 is an aromatase inhibitor (AI) with a well-established, multi-year chronic safety and tolerability profile.
Methazolamide
go.drugbank.com/drugs/DB00703ApprovedA carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Categories: Heterocyclic Compounds, 1-RingTaliglucerase alfa
go.drugbank.com/drugs/DB08876ApprovedIt was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease. … Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase.
Synonyms: prGC-DProducts: ELELYSO 200 U İNFÜZYONLUK SOLÜSYON İÇİN LİYOFİLİZE TOZ, 1 ADETRifapentine
go.drugbank.com/drugs/DB01201ApprovedInvestigationalRifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. … Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycinCopper oxodotreotide Cu-64
go.drugbank.com/drugs/DB15873Approved[A220348] In a head-to-head trial, the former tracer detected twice as many lesions as the latter.[A220348] … Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over <sup>68</sup>Ga-labeled somatostatin analogs for positron emission tomography (PET).
Centanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigational[L63806] Its mechanism in ADHD is unclear, but its efficacy may be mediated by this triple reuptake inhibition, which increases the availability of all three neurotransmitters in pathways involved in attention … reuptake inhibitor, positioning it as a new mechanistic option in a condition where response varies widely between individuals and many patients remain symptomatic on existing treatment.
Primaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigationalIt has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. … An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline, 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinolinePolydextrose
go.drugbank.com/drugs/DB14836ExperimentalPolydextrose is under investigation in clinical trial NCT02258750 (Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety).
Categories: Compounds used in a research, industrial, or household setting