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Cycliramine
go.drugbank.com/drugs/DB20968ExperimentalCycliramine is a small molecule drug. Cycliramine has a monoisotopic molecular weight of 298.12 Da.
Falipamil
go.drugbank.com/drugs/DB20969ExperimentalFalipamil is a small molecule drug. Falipamil has a monoisotopic molecular weight of 428.23 Da.
Categories: Heterocyclic Compounds, 2-RingDoqualast
go.drugbank.com/drugs/DB20974ExperimentalDoqualast is a small molecule drug. Doqualast has a monoisotopic molecular weight of 240.05 Da.
Categories: Heterocyclic Compounds, 2-RingAcetryptine
go.drugbank.com/drugs/DB20978ExperimentalAcetryptine is a small molecule drug. Acetryptine has a monoisotopic molecular weight of 202.11 Da.
Lenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigational[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1H-CYCLOPROPA(3,4)CYCLOPENTA(1,2-C)PYRAZOLE, N-((1S)-1-(3-(4-CHLORO-3-((METHYLSULFONYL)AMINO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-METHYL-3-(METHYLSULFONYL)-1-BUTYN-1-YL)-2-PYRIDINYL)-2-(3,5-, N-((1S)-1-(3-(4-CHLORO-3-(METHANESULFONAMIDO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-(METHANESULFONYL)-3-METHYLBUT-1-YN-1-YL)PYRIDIN-2-YL)-2-(3,5- DIFLUOROPHENYL)ETHYL)-2-((3BS,4AR)-5,5-DIFLUOROImlunestrant
go.drugbank.com/drugs/DB19043ApprovedInvestigationalImlunestrant is a brain-penetrant selective estrogen receptor antagonist and degrader. … The FDA approved imlunestrant on September 25, 2025 [L54051] as a treatment for estrogen receptor (ER)-positive, HER2-negative, estrogen receptor 1 (ESR1)-mutated advanced or metastatic breast cancer with
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (5r)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5h-(1)benzopyrano(4,3-c)quinolin-2-ol, 5h-(1)benzopyrano(4,3-c)quinolin-2-ol, 5-(4-(2-(3-(fluoromethyl)-1-azetidinyl)ethoxy)phenyl)-8-(trifluoromethyl)-, (5r)-Sevabertinib
go.drugbank.com/drugs/DB21667ApprovedInvestigational[L64186] Sevabertinib functions as a reversible kinase inhibitor of human epidermal growth factor receptor 2 (HER2), also exhibiting activity against epidermal growth factor receptor (EGFR). … [L54638] Sevabertinib was granted accelerated approval by the FDA on November 19th, 2025 for patients who had received a prior systemic therapy.
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsGadoquatrane
go.drugbank.com/drugs/DB33282ApprovedGadoquatrane is a macrocyclic gadolinium-based contrast agent used to enhance magnetic resonance imaging. … [L63814] Like other gadolinium agents it is paramagnetic, developing a magnetic moment in the scanner's field that alters the relaxation of nearby water protons and brightens tissues with abnormal vascularity
Potrasertib
go.drugbank.com/drugs/DB21682ExperimentalPotrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Potrasertib is a serine/threonine kinase inhibitor. … Potrasertib has a monoisotopic molecular weight of 564.19 Da.
Frespaciguat
go.drugbank.com/drugs/DB21683InvestigationalFrespaciguat is a small molecule drug. The usage of the INN stem '-ciguat' in the name indicates that Frespaciguat is a guanylate cyclase activator and stimulator. … Frespaciguat has a monoisotopic molecular weight of 608.14 Da.