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Displaying results 4051 - 4060 of 7018 in total
  1. Drug

    Estramustine phosphate

    go.drugbank.com/drugs/DB14674
    Approved

    A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.

  2. Drug

    Aganirsen

    go.drugbank.com/drugs/DB15369
    Investigational

    Aganirsen is under investigation in clinical trial NCT02947867 (Trial of Aganirsen in iCRVO Patients at Risk of Developing NVG).

  3. Drug

    Phosphonoacetic Acid

    go.drugbank.com/drugs/DB02823
    Experimental

    A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]

  4. Drug

    Ninvosudil

    go.drugbank.com/drugs/DB08756
    Investigational

    Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.

  5. Drug

    Apramycin

    go.drugbank.com/drugs/DB04626
    InvestigationalVet approved

    Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.

  6. Drug

    Pegvisomant

    go.drugbank.com/drugs/DB00082
    ApprovedInvestigational

    Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly.

  7. Drug

    Tyrosinase

    go.drugbank.com/drugs/DB16626
    Investigational

    as melanogenesis). … [A231829, A231834, A231839] Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis (also known

    Synonyms: Tumor rejection antigen AB
  8. Drug

    Siltuximab

    go.drugbank.com/drugs/DB09036
    ApprovedInvestigational

    It is administered as a 1 hour intravenous infusion every 3 weeks. … Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology.

  9. Drug

    AT9283

    go.drugbank.com/drugs/DB05169
    Investigational

    AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.

  10. Drug

    Metralindole

    go.drugbank.com/drugs/DB09306
    Experimental

    Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A.