Estramustine phosphate

DB14674ApprovedSmall molecule

A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.

Chemical structure of Estramustine phosphate
Mechanism
Curator reviewed
Formula / weight
C23H32Cl2NO6P · 520.38 g/mol (avg)
Code names
BRN 1898199 · Leo 299 · LS-299 · NSC-89199

Resolves to

Compound
UNIIMUZ9585Y7BCAS4891-15-0ChEMBLCHEMBL1756ChEBI68643
Clinical / RWD
RxNorm105556
Structure
InChIKeyADFOJJHRTBFFOF-RBRWEJTLSA-NSMILES[H][C@@]12CC[C@H](OP(O)(O)=O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(OC(=O)N(CCCl)CCCl)C=C3
Targets
P10275ARP11137MAP2P10636MAPTQ06124PTPN11

What you can answer from here — as of July 07, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
38Drug interactionsStructured to mechanism, not free text
Sign in
6Clinical trialsPhase, status and sponsor resolved per trial
Sign in
10+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Estramustine phosphate, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In