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Aleglitazar
go.drugbank.com/drugs/DB08915InvestigationalAleglitazar is an investigational drug from the company Hoffmann–La Roche and is currently in a phase III clinical trial called ALECARDIO. … It is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity.
Categories: Heterocyclic Compounds, 1-Ring(4R)-limonene
go.drugbank.com/drugs/DB08921InvestigationalAs the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant … Limonene is common in cosmetic products.
Synonyms: (R)-4-isopropenyl-1-methyl-1-cyclohexene, (R)-1-methyl-4-(1-methylethenyl)cyclohexeneChlorcyclizine
go.drugbank.com/drugs/DB08936ApprovedChlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. … Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can be used as an antiemetic.
Mixtures: biclora-D, biclora-DCategories: Heterocyclic Compounds, 1-RingTAS-102
go.drugbank.com/drugs/DB08937InvestigationalTAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. … It is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine. Trifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis.
Categories: Heterocyclic Compounds, 1-RingIsoxsuprine
go.drugbank.com/drugs/DB08941ApprovedWithdrawnIt is used in the treatment of peripheral vascular disease and in premature labor. … A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
Categories: 2-Amino-1-Phenylethanol DerivativesIsoxicam
go.drugbank.com/drugs/DB08942ApprovedWithdrawnIsoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingIndenolol
go.drugbank.com/drugs/DB08952ApprovedWithdrawnIndenolol is a drug of the beta-adrenergic blocker class.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesFendiline
go.drugbank.com/drugs/DB08980ApprovedWithdrawnFendiline is non-selective. … Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SENSIT FEnviomycin
go.drugbank.com/drugs/DB08993ExperimentalIt is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.
Synonyms: Tuberactinomycin N