Chlorcyclizine

DB08936ApprovedSmall moleculeHistamine Antagonists

Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can...

Chemical structure of Chlorcyclizine
Mechanism
Curator reviewed
Formula / weight
C18H21ClN2 · 300.826 g/mol (avg)
Code names
Compound 47-282
Brand names
  • Ahist Antihistamine
  • Biclora
  • Bonine for Kids
  • Stahist Ad Liquid

Resolves to

Compound
UNIIM26C4IP44PCAS82-93-9ChEMBLCHEMBL22150ChEBI94402PubChem2710
Clinical / RWD
RxNorm2354ATCR06AE04
Structure
InChIKeyWFNAKBGANONZEQ-UHFFFAOYSA-NSMILESCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=C(Cl)C=C1
Targets
P35367HRH1

What you can answer from here — as of August 30, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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866Drug interactionsStructured to mechanism, not free text
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1Clinical trialPhase, status and sponsor resolved per trial
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6Structured indicationsCondition, population, route and combination as fields, not prose
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19Marketed productsAcross 1 country and 9 labellers
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1ATC codeIncluding every combination product, plus 8 drug categories
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4+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Chlorcyclizine, and which of those have an active Phase 3 trial?

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