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Tegoprazan
go.drugbank.com/drugs/DB16690Investigational[A234215, A234220] Tegoprazan’s strong and sustained effect is due to its ability to be slowly cleared from the gastric glands and exertion of effects independent of acid levels. … [A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB) with a fast onset of action and the ability to control gastric pH for a prolonged period of time.
Synonyms: K-CABCategories: Alimentary Tract and Metabolism, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Rucaparib
go.drugbank.com/drugs/DB12332ApprovedInvestigationalBy targeting the genetically-mutated cancer cells that lack a DNA repair mechanism, rucaparib causes cancer cell death and reduces tumour growth. … [A249240] The drug was later approved by the European Commission in May 2018.[L42185] It is currently used to treat recurrent ovarian and prostate cancer in adults.[L42155,L42185].
Categories: Antineoplastic and Immunomodulating AgentsAlglucosidase alfa
go.drugbank.com/drugs/DB01272ApprovedInvestigationalAlglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages of lysosomal glycogen. … It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients.
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismProducts: (Alglucosidase alfa) 50mg Powder for Solution for InfusionDelamanid
go.drugbank.com/drugs/DB11637ApprovedInvestigationalDelamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall [A31965]. … Delamanid is approved by the EMA and is marketed under the trade name Deltyba as oral tablets. It is marketed by Otsuka Pharmaceutical Co., Ltd (Tokyo, Japan).
Human interferon beta
go.drugbank.com/drugs/DB14999ApprovedInvestigationalHuman interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. … [A191784] Interferon beta is currently being studied as a possible treatment for COVID-19, which results from infection with the novel 2019 SARS-CoV-2 virus.
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsAurothioglucose
go.drugbank.com/drugs/DB09121ApprovedWithdrawnThe use of gold compounds has decreased since the 1980s owing to numerous side effects, limited efficacy, and slow onset of action. … Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis [A32326].
Categories: Antiinflammatory and Antirheumatic ProductsProducts: Solganal Inj 50mg/mlFludeoxyglucose (18F)
go.drugbank.com/drugs/DB09502ApprovedInvestigationalIt is administered by intravenous injection.
Categories: Indicators and ReagentsTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigational[A253717] By binding to CTLA-4, tremelimumab enhances T cell-mediated killing of tumours and reduces tumour growth. … [A253717, L43652] Because CTLA-4 is an immune checkpoint that plays a vital role in regulating T cell-mediated immune response, tremelimumab is considered an immune checkpoint inhibitor, which is an emerging
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsMilsaperidone
go.drugbank.com/drugs/DB24348ApprovedInvestigational[L56056] Atypical antipsychotic agents work by blocking the D2 dopamine and serotonin receptor signalling pathways. … [L56056] On February 20, 2026, milsaperidone was approved by the FDA for the treatment of Bipolar I Disorder and schizophrenia.[L56059]
Zuranolone
go.drugbank.com/drugs/DB15490ApprovedInvestigationalThis approval was based on favorable results from 2 phase 3 clinical trials.[L47691] … [A260791] Zuranolone was approved by the FDA on August 4th, 2023, and it is currently the only approved treatment for women with postpartum depression.