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Tisotumab vedotin
go.drugbank.com/drugs/DB16732ApprovedInvestigational[L38429] Tisotumab vedotin-tftv is marketed under the trade name Tivdak as an intravenous injection. On April 29, 2024, tisotumab vedotin was granted full FDA approval. … Each monoclonal antibody molecule carries an average of four MMAE molecules. Tisotumab vedotin is the first TF-directed ADC [A238914] that works by binding to TFs expressed on solid tumours.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesRaclopride
go.drugbank.com/drugs/DB12518InvestigationalRaclopride has been used in trials studying Parkinson Disease.
Categories: Dopamine D2 Receptor AntagonistsPrednylidene
go.drugbank.com/drugs/DB13208ExperimentalPrednylidene is an experimental systemic glucocorticoid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersTetramisole
go.drugbank.com/drugs/DB16561InvestigationalTetramisole is an anthelmintic agent.[A275223]
Synonyms: Levamisole DL-formAgalsidase alfa
go.drugbank.com/drugs/DB15874ApprovedInvestigationalWhile patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.
Synonyms: alpha-D-galactosidase, alpha-D-galactopyranosidaseDithiazanine
go.drugbank.com/drugs/DB11516ApprovedVet approvedWithdrawnHowever, its use is severely limited due to its toxicity. Dithiazanine iodide was associated with eight fatal cases of severe acidosis and shock between 1961 and 1964.
Hexocyclium
go.drugbank.com/drugs/DB06787ApprovedProton pump inhibitors like [DB00338] and opiate anti-diarrheal agents like [DB00836] have largely replaced the use of anti-muscarinics in the treatment of gastric ulcers and diarrhea due to their more
Narasin
go.drugbank.com/drugs/DB11432ExperimentalVet approvedNarasin is an agent with coccidiostatic and antibacterial properties.
Farabursen
go.drugbank.com/drugs/DB18127InvestigationalRGLS-8429 is an investigational anti-miR-17 oligonucleotide.