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Icosapent
go.drugbank.com/drugs/DB00159ApprovedInvestigationalNutraceuticalImportant polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovas...
Mixtures: TL-Care DHA, GNC SALMON OIL 1000Delgocitinib
go.drugbank.com/drugs/DB16133ApprovedInvestigationalDelgocitinib is a pan-Janus kinase (JAK) inhibitor. After the first global approval in Japan, delgocitinib was also approved by the European Commission on September 23, 2024. It works to reduce the inflammatory response in inflammatory s...
Dimethicone
go.drugbank.com/drugs/DB11074ApprovedInvestigationalDimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties.
Mixtures: Spasmo Nil Tab, Hand and Nature Anti Wrinkle Hand Aragon OilProducts: OBERON MOMS CARE OIL, OBERON MOMS CARE BODY OILFosfomycin
go.drugbank.com/drugs/DB00828ApprovedInvestigational[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration.
Polyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approvedPolyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a rati...
Mixtures: SELG, SELGVanzacaftor
go.drugbank.com/drugs/DB18373ApprovedInvestigationalVanzacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It is used alongside other CFTR correctors and CFTR potentiators to increase the quantity and function of CFTR at the cell surface in p...
Metamfetamine
go.drugbank.com/drugs/DB01577ApprovedIllicitInvestigationalWithdrawnThe FDA withdrew its approval for the use of all parenteral drug products containing methamphetamine hydrochloride, a metamfetamine salt.[L43942]
Simethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigationalSimethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in ...
Mixtures: SAL DE FRUTAS LUA PLUS, SAL DE FRUTAS LUA PLUSNilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalNilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered si...
alpha-Linolenic acid
go.drugbank.com/drugs/DB00132ApprovedInvestigationalNutraceuticalWithdrawnAlpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Mixtures: Flaxseed Oil Capsules