Dimethicone is an ingredient used to treat dry and irritated eyes.
- Brand Names
- A+d Diaper Rash, Alka-seltzer Heartburn Plus Gas Relief, Almacone, Carlesta, Dyna1199 with Dimethicone, Dynashield, Gelusil, Gold Bond Maximum Relief, Imodium Multi-symptom Relief, Maalox Plus, Mi-acid, Mi-acid Double Strength, Mintox Plus, Mylanta, Mylanta Tonight, Pediacare Gas Relief, Phazyme, Rash Relief Antibacterial, Rash Relief Antifungal, Rash Relief With Zinc Oxide, Rolaids Advanced, Titralac Plus
- Generic Name
- DrugBank Accession Number
Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products. On skin, it is also observed to have moisturizing actions 6,8.
A study found that that the 100 % dimethicone product is a safe and highly effective head lice treatment for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing products 3.
- Small Molecule
- External IDs
- Dow Corning 1664
Dimethicone is a colorless liquid with both cosmetic and therapeutic uses. It is used in topical creams and ointments to help distribute the active ingredients. Dimethicone is used as an anti-foaming agent, a hair and skin conditioner, and in the treatment of head lice and, as an anti-bloating/anti-flatulence agent 2, 7.Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset
- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
- Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects
This drug acts as a skin protectant by helping to treat and prevent minor skin irritation due to diaper rash and seals out moisture from the diaper area. This drug temporarily protects and helps prevent chafed, chapped, cracked or windburned skin. 7.
- Mechanism of action
When applied topically, dimethicone forms a layer to delay the evaporation of water 8. In the treatment of head lice dimethicone 100, the respiratory systems of head lice are targeted. NYDA works by suffocating the lice, nymphs and the embryos. The physical properties of this drug, including the viscosity and spreading property of the solution allow it to easily flow into the respiratory system of all developmental stages of the insect, causing suffocation and death of the organisms. It diffuses through the stigmata (spiracles) of the lice, into the tracheae of the head lice as well as through the aeropyles of the egg operculum. The solution then displaces oxygen. The low viscosity, volatile dimethicone enables the NYDA head lice solution to penetrate into the breathing system. Its evaporation causes the thickening of the NYDA solution. The remaining high viscosity dimethicone ultimately encloses the respiratory system and thus leading to suffocation of all stages of head lice (adult lice, larvae and eggs). This mode of action prevents the development of lice resistance by preventing the formation of new progency 9.
Studies performed using house crickets and lice suggest a close correlation between the death of the lice and the influx of the solution into the insect head tracheae. These data strongly suggest that the total filling of the head tracheae immediately blocks the oxygen supply to the insect central nervous system. Death, following numerous stages of disability after the entrance of dimethicones into the abdominal tracheal system, demonstrates the sequence of oxygen deprivation. NYDA was applied directly to the head and mouth of the organism, and was found to have no effect when applied solely to the outside of the head/mouth 9.
This drug is not believed to be absorbed when used in quantities from 1-30% Label.
- Volume of distribution
Following injection of [14C]dimethicone fluid in the hind limb of rats, the radioactivity was distributed primarily in the gastrointestinal tract, and no evidence of metabolism was observed. When [14C]dimethicone was administered through i.p. injection in rats, the following distribution of radioactivity was observed at 25 days after dosing: 51% in adipose tissue, 27% in gastrointestinal tissues, and 15% in liver 5.
- Protein binding
- Not Available
- Route of elimination
- Adverse Effects
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The minimum lethal oral dose of dimethicone 200 (50 cs), dimethicone 550 (75 cs), dimethicone in rats 5.
A 76-week dietary toxicity study of a silicone antifoam compound (94% polydimethylsiloxane silicone oil and 6% silicone dioxide) was performed in mice. Three groups were given diet containing 0, 0.25%, or 2.5% of the test article. The dose levels in the treatment groups were estimated to be 580 and 5800 mg/kg/day. Mortality was increased in the 5800 mg/kg/day females. No target organs of toxicity were observed. The no-effect dose was 580 mg/kg/day. This study is of limited usefulness for assessing the toxicity of dimethicones, due to the small number of organs/tissues that were examined 5.
In one clinical study, 145 subjects were treated with either NYDA (dimethicone )or with a permethrin-based lice product. The number of subjects experiencing any adverse events was similar in both groups. In the NYDA group, 29 adverse events were reported in 25 subjects. All except two adverse events were categorized as being unrelated to the lice treatment (e.g., superficial wound after a fall, otitis externa following swimming in a pool). Two patients in the NYDA group experienced ocular irritation after treatment when the product entered the eyes. The irritation resolved spontaneously in both cases after rinsing the eyes with clean water 9.
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
- Food Interactions
- No interactions found.
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- Product Ingredients
Ingredient UNII CAS InChI Key Dimethicone 100 RO266O364U 9006-65-9 Not applicable
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image 28 Remedy Balancing Day Moisturizer Cream 0.45 mg/45mL Topical NoTS Co.,Ltd 2015-03-01 2018-12-01 28 Remedy Repair Cream 0.3 g/30g Topical NoTS Co Ltd 2015-03-01 2018-12-01 28 Remedy Repair 30g Cream 0.3 g/30g Topical NoTS Co.,Ltd 2016-01-02 2018-12-01 3ce Lip Lacquer Backstage Lipstick 0.76 g/6.4g Topical Nanda Co., Ltd 2016-08-01 2018-12-01 3ce Lip Lacquer Bon Bon Lipstick 0.76 g/6.4g Topical Nanda Co., Ltd 2016-08-01 2018-12-01 3ce Lip Lacquer Dahlia Lipstick 0.76 g/6.4g Topical Nanda Co.,Ltd 2016-08-01 2018-12-01 3ce Lip Lacquer Dis Co Lipstick 0.76 g/6.4g Topical Nanda Co.,Ltd 2016-08-01 2018-12-01 3ce Lip Lacquer Fever Lipstick 0.76 g/6.4g Topical Nanda Co.,Ltd 2016-08-01 2018-12-01 3ce Lip Lacquer Hawaiian Pink Lipstick 0.76 g/6.4g Topical Nanda Co.,Ltd 2016-08-01 2018-12-01 3ce Lip Lacquer Pink Boom Lipstick 0.76 g/6.4g Topical Nanda Co.,Ltd 2016-08-01 2018-12-01
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image A + D Diaper Rash Cream Dimethicone (1 %) + Zinc oxide (10 %) Cream Topical Schering Plough 2010-04-05 2014-07-31 A AND A Diaper Rash cream Dimethicone (10 mg/1g) + Zinc oxide (100 mg/1g) Cream Topical BioZone Laboratories, Inc. 2013-06-15 Not applicable A and D Dimethicone (11.09 mg/1g) + Zinc oxide (110.09 mg/1g) Cream Topical Bayer Healthcare Llc. 2009-12-25 Not applicable ABC Arbonne Baby Care Diaper Rash Dimethicone (1 g/100g) + Zinc oxide (12 g/100g) Cream Topical Arbonne International Llc 2014-09-20 Not applicable Abc Arbonne Baby Care Diaper Rash Cream Dimethicone (1 %) + Zinc oxide (12 %) Cream Topical Arbonne International Llc 2014-09-25 Not applicable ABC Arbonne Baby Care Kit Dimethicone (1 g/100g) + Zinc oxide (144 mg/1mL) + Zinc oxide (12 g/100g) Kit Topical Arbonne International, LLC 2014-09-20 Not applicable ABC Arbonne Baby Care Little Bundles Set Dimethicone (1 g/57g) + Zinc oxide (14.4 mg/100mL) + Zinc oxide (12 g/57g) Topical Arbonne International, LLC 2015-09-01 2015-10-16 ABC Arbonne Baby Care Little Bundles Set Dimethicone (1 %) + Zinc oxide (12 %) Cream; Kit Topical Arbonne International Llc 2015-09-01 2016-12-21 ABC Arbonne Baby Care Sample Set Dimethicone (1 mg/3mL) + Zinc oxide (14.4 mg/3mL) + Zinc oxide (12 mg/3mL) Kit Topical Arbonne International Llc 2016-04-15 Not applicable AdipoWin Dimethicone (5 mg/1mL) + Glycerin (60 mg/1mL) Cream Topical Supadelixir Co Ltd 2017-01-02 Not applicable
- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 3ce Matte Lip Crayon Dubious Dimethicone (0.006 g/1g) Lipstick Topical Nanda Co., Ltd. 2016-08-10 Not applicable AQUTOP Moisturizing Signature Tone-up Cream Dimethicone (0.53 g/50mL) + Adenosine (0.02 g/50mL) + Nicotinamide (1 g/50mL) Cream Topical Alable Co., Ltd. 2018-07-09 Not applicable BEYOND THE SHAVE For Men Dimethicone (2.9 g/100mL) + Allantoin (0.5 g/100mL) + Avobenzone (3.0 g/100mL) + Homosalate (2.5 g/100mL) + Octasulfur (3.0 g/100mL) + Octisalate (5 g/100mL) + Octocrylene (2.7 g/100mL) Kit Topical Rodan & Fields 2017-06-01 Not applicable Biellee Pollen Hydra Pure Brightening Cream Dimethicone (0.4 mg/50mL) Cream Topical Nsb Co., Ltd. 2016-06-21 Not applicable Cellapy A.Repair Plus Dimethicone (0.85 g/50mL) + Nicotinamide (1 g/50mL) + Panthenol (0.1 g/50mL) Cream Topical Gm Holdings Co., Ltd 2017-01-04 Not applicable DEARSIR Aqua Shuttle Essence Skin Dimethicone (0.96 g/140mL) + Glycerin (2.32 g/140mL) Liquid Topical Celltrion Skincure Co.,ltd. 2017-07-01 2018-12-01 DEARSIR Perfection Fluid Dimethicone (0.81 g/130mL) + Glycerin (6.50 g/130mL) Cream Topical Celltrion Skincure Co.,ltd. 2017-07-01 2018-12-01 DermacinRx Clorhexacin Dimethicone (50 mg/1mL) + Chlorhexidine gluconate (4 g/100mL) + Mupirocin (20 mg/1g) Kit Topical PureTek Corporation 2016-06-02 Not applicable DermacinRx Surgical ComboPak Dimethicone (50 mg/1mL) + Chlorhexidine gluconate (4 g/100mL) Kit Topical PureTek Corporation 2015-04-28 Not applicable DermacinRx Surgical PharmaPak Dimethicone (50 mg/1mL) + Chlorhexidine gluconate (4 g/100mL) + Mupirocin (20 mg/1g) Kit Topical PureTek Corporation 2015-08-27 Not applicable
- ATC Codes
- P03AX05 — Dimeticone
- Drug Categories
- Antifoaming Agents
- Antiparasitic Products, Insecticides and Repellents
- Basic Ointments and Protectants
- Compounds used in a research, industrial, or household setting
- Ectoparasiticides, Incl. Scabicides
- Ectoparasiticides, Incl. Scabicides, Insecticides and Repellents
- Macromolecular Substances
- Misc. Skin and Mucous Membrane Agents
- Organosilicon Compounds
- Scabicides and Pediculicides
- Silicon Compounds
- Skin Barrier Activity
- Not classified
- Affected organisms
- Not Available
- CAS number
- InChI Key
- Not Available
- Not Available
- IUPAC Name
- Not Available
- Not Available
- General References
- Ingram RJ, Bartlett A, Brown MB, Marriott C, Whiffield RJ: Dimethicone barrier cream prevents infection of human skin by schistosome cercariae: evidence from Franz cell studies. J Parasitol. 2002 Apr;88(2):399-402. doi: 10.1645/0022-3395(2002)088[0399:DBCPIO]2.0.CO;2. [Article]
- Dimethicone [Link]
- Safety and efficacy of a 100 % dimethicone pediculocide in school-age children [Link]
- Public Assessment Report, Dimethicone [Link]
- CENTER FOR DRUG EVALUATION AND RESEARCH- 20755 [Link]
- Dimethicone [Link]
- Moisturel, Daily Med monograph [Link]
- Guidelines of care for the management of atopic dermatitis [Link]
- Product Monograph, NYDA [Link]
- POLYDIMETHYLSILOXANE [Link]
- Dimethicone [Link]
- DailyMed Label: DIMETHICONE, skin protectant cream [Link]
- AHFS Codes
- 56:10.00 — Antiflatulents
- 84:24.12 — Basic Ointments and Protectants
- 84:92.00 — Misc. Skin and Mucous Membrane Agents
- 84:04.12 — Scabicides and Pediculicides
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Diagnostic Bowel preparation therapy / Colonoscopy 1 4 Completed Diagnostic Premature Births 1 4 Completed Prevention 13-valent Pneumococcal Vaccine / Immunizations / Premature Births / Safety 1 4 Completed Prevention Flu caused by Influenza 1 4 Completed Treatment Dentin Sensitivity / Periodontal Diseases 1 4 Completed Treatment Gastro-esophageal Reflux Disease (GERD) 1 4 Completed Treatment Postoperative pain 1 4 Recruiting Prevention Chronic Infection / Congenital Malformations / Fetal Malformation / Hepatitis B Infection / Viral sepsis 1 4 Recruiting Prevention Stillbirths and Infant Mortality 1 4 Terminated Treatment Relapsing Remitting Multiple Sclerosis (RRMS) 1
- Not Available
- Not Available
- Dosage Forms
Form Route Strength Lipstick Topical 0.76 g/6.4g Lipstick Topical 0.006 g/1g Cream Topical 0.93 g/30mL Cream Topical 0.75 g/50mL Stick Topical 0.1 g/100g Stick Topical 0.85 g/100g Cream Topical 13000 mg/1L Cream; kit Topical Suspension Intra-articular; Oral Cream Cutaneous 0.5 mg/50mL Cream Cutaneous 2 mg/100mL Cream Cutaneous 1.2 mg/30mL Cream Topical 1.375 g/55mL Cream Topical 0.3 g/25mL Cream Topical 1.32 g/120mL Cream Topical 0.48 g/40mL Lotion Topical 10 mg/1g Capsule, liquid filled Not applicable 125 mg/1 Cream Topical 1.95 g/150mL Cream Topical 4 mg/1mL Cream Cutaneous 0.9 g/45g Cream Cutaneous 0.45 g/45g Cream Cutaneous 0.45 mL/45mL Cream Topical 1.35 g/50mL Cream Topical 0.75 g/25mL Tablet, chewable Oral Lotion Topical 30 mg/1mL Lotion Topical 3.54 g/118mL Lotion Topical 7.08 g/236mL Lotion Topical 1.77 g/59mL Lotion Topical .03 mg/1mL Cloth Topical 0.352 g/1 Cream Topical 2.1 g/100mL Cream Topical 0.65 g/50g Cream Cutaneous 0.51 mL/50mL Patch Topical 0.6 g/20g Liquid Oral 21 mg/100mL Capsule Oral 125 mg/1 Lotion Topical 4.55 g/130mL Cream Topical 0.2 g/20g Oil Topical 249.2 mg/1mL Cream Topical 1 g/100mL Cream Topical 0.01 g/100mL Solution Topical 30 mg/300mL Cream Topical 20 mg/200mL Stick Topical 0.9 g/10g Cream Topical 0.60 mg/60g Lotion Topical 13 mg/1g Cream Topical 12.5 mg/1g Cream Topical 13 mg/1g Kit Topical 12 mg/1mL Lotion Topical 12 mg/1mL Cream Topical 125 mg/1g Emulsion Topical 50 mg/1g Spray, suspension Topical Cream Topical 3 g/100g Lotion Topical 1.2 g/100mL Lotion Topical 0.5 g/100mL Lotion Topical 1.2 g/100g Cream Topical 0.2 g/1g Cream Topical Lotion Topical 2 g/100mL Lotion Topical Cloth Topical 3 g/100g Lotion Topical 20 mg/1g Cream Topical 1 g/50g Cream Topical 1.6 g/160g Lotion Topical 1.25 g/100mL Liquid Topical 2.5 g/50mL Cream Topical 0.5 g/50mL Cream Topical 2.93 g/125mL Cream Topical 1.5 g/30mL Aerosol Topical 2.7 g/100g Jelly Topical 2 g/100g Cream Topical 2.25 g/150mL Cream Topical 1.25 g/50mL Cream Topical 0.3 g/30mL Cream Cutaneous 2.72 g/50g Tablet Oral 125 mg/1 Cream Topical 0.4 mg/50mL Cream Topical 1.02 mg/40mL Tablet Cream Cutaneous 0.5 mL/50mL Cream Topical 4.27 g/95g Patch Topical 0.96 mg/32mL Cream Topical 0.015 g/1mL Cream Topical 0.15 g/15mL Stick Topical 10 mg/1g Ointment; stick Topical Kit Topical Cream Topical 5.88 mg/5.88mL Cream Topical 4.4 g/44g Stick Topical 0.01 g/1g Liquid Topical 2.5 g/100mL Cream Topical 0.5 g/50g Cream Topical 0.6 g/20g Liquid Topical 32 mg/100g Liquid Topical 3.2 g/100g Cream Topical 0.82 mg/55mL Emulsion Topical 1.20 mg/120mL Cream Topical 0.55 mg/55mL Cream Topical 1.65 g/55mL Cream Topical 2.2 g/55mL Cream Topical 1.2 g/60mL Cream Topical 2.4 g/60mL Cream Topical 0.2 mg/20mL Cream Topical 0.7 mg/70mL Lotion Topical 1.50 g/150mL Cream Topical 1.50 g/150mL Cream Topical 2.8 mg/140mL Cream Topical 0.51 mg/15mL Cream Topical 0.9 g/35mL Cream Topical 1.14 g/55mL Cream Topical 10.04 g/200mL Cream Topical 0.9 g/30mL Cream Topical 2.3 g/50mL Ointment Topical 0.36 g/30g Cream Topical 0.4 mg/40mL Cream Topical 0.3 mg/30mL Cream Topical 12 mg/1g Lotion Topical 10 mg/1mL Lotion Topical 20 mg/1mL Cream Topical 3.90 g/65mL Stick Topical Gel Topical 20 mg/1g Cream Topical 6.0 mg/30mL Liquid; spray Topical Liquid Topical 1.52 mg/1mL Lotion Topical 1.25 mg/100mL Cloth Topical Cloth Topical 30 mg/1g Gel Topical 2.5 g/50mL Liquid Topical 3.6 g/120mL Cream Topical 0.57 g/57g Stick Topical 0.66 g/8.5g Stick Topical 1 g/100g Liquid Topical 12 mg/1mL Cream Topical 12.5 mg/1mL Spray Topical 1 g/100mL Lotion Topical 12.12 mg/1mL Lotion Topical 13.1 mg/1g Lotion Topical 1.3 g/100g Lotion Topical 1.3 kg/100mL Lotion Topical 13.13 mg/1mL Lotion Topical 1.2500 mL/100mL Cream Topical 0.2 g/100g Cream Topical 2.92 g/75mL Lotion Topical 0.01 g/1mL Kit Cutaneous; Topical Cream Topical 3 g/100mL Cream Topical .01 mg/1g Lotion Topical 0.5 g/100g Lotion Topical 1.0 g/100g Capsule, coated Oral Cream Topical 17.5 ug/1mg Cream Topical 50 ug/1mg Liquid Topical 17.5 ug/1mg Ointment Topical Disc Topical Lotion Topical 4.50 mg/300mL Cream Topical 5.5 g/110mL Liquid Topical 1.5 g/30mL Cream Topical 6.0 g/100mL Lotion Topical 1.1 g/100mL Cream Topical Cream Topical 0.9 g/30g Oil Topical 26 1/100mL Oil Topical 1.5 1/150mL Cream Topical 11.5 g/50g Cream Topical 15 mg/1g Gel Topical 1.27 g/100mL Cream Topical 6.0192 g/100mL Cream Topical 0.5 g/100mL Cream Topical 0.75 g/100mL Gel Topical 0.01 g/100mL Liquid Topical 0.01 g/100mL Liquid Topical 1.2 g/100mL Cream Topical 4.0 g/400mL Granule, effervescent Oral Tablet Oral 40 mg/1 Solution Topical 12.0 mg/200mL Liquid Topical 9.60 g/200mL Liquid Topical 2.88 g/60mL Cream Topical 0.9 g/60mL Cream Topical 0.46 mg/40mL Cream Topical 0.9 g/45g Emulsion Topical 2 mg/1g Cream Topical 20 g/1000g Solution Oral Lotion Topical 13 mg/1mL Suspension / drops Oral 20 mg/0.3mL Gel Topical 30 g/100mL Cream Cutaneous 0.55 g/55g Tablet, chewable Oral Kit Topical 5 g/100g Liquid Oral 125 mg/5mL Capsule, gelatin coated Oral 125 mg/1 Cream Cutaneous Tablet, chewable Oral 80 mg/80mg Cream Topical 0.8 g/80mL Cream Topical 0.62 mg/20mL Patch Cutaneous 4 g/100g Capsule, coated pellets Oral Gel Topical 2 g/100mL Liquid Topical 3.1 mg/155mL Lotion Topical 0.5 mg/1mL Gel Topical 3.2 g/100g Aerosol, foam Topical 1 g/100g Cream Topical 5.45 g/125mL Cream Topical 0.46 g/20mL Cream Topical 0.605 g/55mL Kit Topical 1.5 g/100mL Cream Topical 2.5 mg/50mL Cream Cutaneous 0.5 g/50g Cream Cutaneous 2.65 mL/50mL Cream Cutaneous 2.25 g/50g Cream Topical 1.39 g/55g Cream Topical 2.64 g/55g Cream Topical 1.88 g/50g Cream Topical 0.71 g/50g Cream Topical 1.54 g/55g Lotion Topical 2.40 mg/130mL Tablet, chewable Oral 125 mg/1 Tablet, chewable Oral 80 mg/1 Capsule Oral 180 mg/1 Strip Oral 62.5 mg/1 Gel Oral 125 mg/1 Gel Oral Lotion Topical 17.5 mg/1mL Cream Topical 17.5 mg/1mL Cream Topical 15 mg/1mL Liquid Topical 0.4 mg/40mL Cream Topical 0.46 g/23mL Cream Cutaneous 1.8 mL/45mL Cream Cutaneous 3.51 mL/45mL Cream Cutaneous 3.69 g/55g Cream Topical 10 mg/1g Cream Topical 0.2 g/50mL Cream Topical 2.0 g/50mL Cream Topical 0.2 g/40mL Cream Topical 1.0 g/50mL Cream Topical 0.83 mg/50mL Cream Topical 1.63 mg/40mL Shampoo Topical 0.6 g/100mL Shampoo Topical 4 mg/400mL Shampoo Topical 2.4 mg/240mL Cream Topical 0.8 g/80g Gel Topical 1 g/100mL Cream Topical 1.5 mL/100mL Cream Topical 1.50 g/60mL Cream Topical 1.01 g/30mL Gel Topical 2 g/300g Gel Topical 1.0 g/300g Cream Topical 0.6 g/30mL Cream Topical 0.5 g/100g Liquid Topical 3 g/100mL Cream Topical 1.04 g/50g Cream Topical 12.5 g/100mL Ointment Topical 17 g/56.69g Lotion / shampoo Topical Cream Topical 2.99 g/50mL Cream Topical 2.08 g/50mL Cream Cutaneous 1.39 g/30mL Lotion Topical 2.0 g/200mL Lotion Topical 12.5 mg/1mL Suspension Oral 20 mg/0.3mL Liquid Oral 20 mg/0.3mL Lotion Topical Liquid Topical 0.15 g/100g Lotion Topical 2.0 mg/200mL Cream Topical 0.96 mg/30mL Cream Topical 0.95 mg/30mL Suspension Shampoo Topical 1 g/100mL Shampoo Topical 1.666667 g/100mL Liquid Topical 1 g/100mL Liquid Topical 0.06 g/1.5mL Cream Topical 0.04 g/1.5mL Liquid Topical 1.5 g/100mL Liquid Topical 1.5 mL/100mL Cream Topical 5.0 mL/100mL Lotion Topical 1.5 mL/100mL Spray Topical 10.2 mg/1mL Liquid Topical 5 g/100mL Gel Topical 0.2 g/10mL Cream Topical 0.75 mg/1mL Lipstick Topical Lipstick Topical 6 g/100g Tablet, chewable Oral 60 mg/1 Tablet Oral Cream Topical 0.58 g/50mL Cream Topical 1.02 g/50mL Aerosol, foam Topical 1 g/100mL Patch Topical Capsule, liquid filled Oral 250 mg/1 Cream Topical 0.1 g/100g Cream Topical 10 g/100g Cream Topical 20 mg/1g Cream Topical 1.5 g/50g Gel Topical 1.05 g/50mL Suspension Oral Lipstick Topical 7.4 g/100g Cream Topical 1.62 mg/65mL Patch Topical 0.16 g/8g Capsule, delayed release Oral Cream Topical 0.3 g/75mL Cream Topical 3 mg/300mL Emulsion Topical 2 mg/200mL Patch Topical 0.22 mg/22mL Cream Topical 0.35 g/35g Cream Topical 2 mg/200mL Cream Topical 7.5 g/150mL Lotion Topical 30 g/1g Lotion Topical 40 mg/1mL Lotion Topical 14.4 mg/1mL Solution / drops Oral 20 mg/0.3mL Gel Topical 1.2 g/100g Gel Topical 12 mg/1g Cream Topical 1 g/50mL Cream Topical 1.5 g/50mL Cream Topical 10 mg/1mL Lotion Topical 4.8 mg/400mL Cream Topical 0.8 g/50mL Gel Topical Capsule Oral Cream Topical 45 mg/1g Patch Topical 0.50 g/20g Stick Topical 0.03 g/3.2g Lotion Topical .02 mL/1mL Cream Topical .02 mL/1mL Cream Topical 50 mg/1mL Cream Topical 1.7 mg/118mg Solution Topical Liquid Topical 1 mg/100mL Lotion Topical 0.15 g/100g Lotion Topical 1 g/100g Lotion Topical 12 mg/1g Lotion Topical 3 g/227g Cream Cutaneous 2 g/50g Liquid Topical 0.03 mg/2.8mL Gel Topical 0.024 g/1mL Cream Topical 7.06 g/50mL Stick Topical 0.09 g/9g Tablet, sugar coated Oral Granule Oral Tablet, coated Oral Lotion Topical 2.70 g/180mL Liquid Oral Emulsion Oral Liquid Topical 1.10 g/110mL Powder, for solution Oral Cream Topical 1.675 g/50g Swab Topical 3.2 g/100g Cloth Topical 32 mg/1mL Capsule, gelatin coated Oral 180 mg/1 Capsule, gelatin coated Oral 250 mg/1 Solution / drops Oral Liquid Oral Capsule, liquid filled Oral 500 mg/1 Cream Topical 0.6 g/60g Cream Topical 1.0 g/20mL Lotion 15 mg/1mL Cream 15 mg/1mL Cream 25 mg/1mL Capsule, gelatin coated Rectal; Vaginal 0.324 g/1.2g Cream Topical 2.38 g/140mL Cream Topical 0.4 g/40mL Cream Topical 0.36 g/30mL Cream Topical 6.75 g/50mL Cream Topical 1.4 g/140mL Cream Topical 1 g/100g Cream Topical 1.6 g/80g Cream Topical 2 g/100g Lotion Topical 3 mg/150mL Cream Cutaneous 1.8 mL/130mL Cream Topical 1.1 g/55mL Cream Topical 0.55 g/50mL Capsule Oral Solution Topical 0.72 g/40mL Swab Topical 32 mg/1g Cream Topical 1.5 mg/30mL Emulsion Topical 2.6 mg/130mL Cream Topical 2.1 mg/60mL Cream Topical 3.05 g/30mL Powder Topical 2.16 g/12g Cream Topical 0.9 mg/30mL Powder Topical 1.85 g/12g Cream Topical 20 mg/1mL Cream Topical 0.01 g/1g Ointment Topical Ointment Topical 0.01 g/1g Cream Topical 1.6 g/80mL Cream Topical 5.41 g/50g Cream Topical 1.25 g/50g Liquid Topical 0.9 g/45mL Cream Topical 8 g/100mL Liquid Topical 8 g/100mL Liquid Topical 53.1 g/100mL Cream Topical 0.3 g/100mL Spray Topical Liquid Topical Cloth Topical 0.608 g/1 Cloth Topical 3.2 % Cloth Topical 0.544 g/1 Cloth Topical 0.294 g/1 Cloth Topical 3.2 g/100mL Cream Topical 0.5 mg/100mL Cream Topical 0.4 g/100mL Shampoo Topical 2 g/100mL Oil Topical 1.2 g/30mL Cream Topical 2.66 g/140mL Cream Topical 1.6 g/40mL Cream Topical 2 g/80mL Cloth Topical 3.6 g/100mL Lotion Topical 1.5 g/100mL Lotion Topical 1.5 mg/100mL Lotion Topical 0.01 g/1g Cream Topical 0.05 g/100g Cream Topical 0.015 g/100g Cream Topical 1.5 g/100mL Cream Topical 1.61 mg/50mL Cream Topical 0.32 g/10mL Cream Topical 1.75 mg/70mL Emulsion Topical 1.3 mg/130mL Cream Topical 0.25 mg/25mL Cream Topical 0.75 mg/50mL Cream Topical 0.15 g/10mL Emulsion Topical 0.2 g/20mL Cream Topical 0.15 mg/15mL Cream Topical 0.03 g/3mL Liquid Topical 1.1 mg/110mL Patch Topical 0.6 g/30mL Liquid Topical 12.5 mg/1mL Bar, chewable Oral Cream Topical 0.3 g/30g Cream Topical 0.6 g/30g Cream Topical 2.49 g/120mL Liquid Topical 2.49 g/120mL Cream Topical 0.54 g/50mL Cream Topical 1.8 g/100mL Gel Topical 1 mg/100mg Lotion Topical 1.25 mL/100mL Cream Topical 1.133 g/113g Cream Topical 960 mg/96g Cream Topical 0.4988 mg/21mL Cream Topical 0.42 mg/21mL Cloth Topical Lotion Topical 50 mg/1mL Powder Topical 0.02 g/10g Cream Topical 0.24 mg/80mL Cream Topical 50 mg/1g Cream Topical 1.0 g/100mL Cream Topical 1.0 mg/100mL Powder Topical 0.08 g/4.5g Powder Topical 0.07 g/4.5g Gel Topical 2.1 g/7.5mL Powder Topical 1.05 g/10g Cream Topical 2.5 g/100mL Suspension Oral Capsule, liquid filled Oral 125 mg/1 Capsule, liquid filled Oral 180 mg/1 Solution / drops Oral Tablet Oral 80 mg/1 Gel Topical .0024 mg/.024mg Gel Topical .00119 mg/.119mg Gel Topical 0.6 mg/60mg Cream Topical 1.04 mg/50mL Lotion Topical 1 mL/100mL Lotion Topical 1.0000 mL/100mL Liquid Topical 1.3 mL/100mL Lotion Topical 5 mg/354mg Ointment Topical 2.272 g/113.6g Stick Topical 1 mg/100mg Gel Topical 1.61 g/50mL Cream Topical 0.5 mg/50mL Emulsion Topical 1.30 mg/120mL Cream Topical 1.07 mg/40mL Emulsion Topical 1.5 g/150mL Cream Topical 0.60 mg/30mL Cream Topical 0.99 g/55mL Emulsion Topical 1.30 g/120mL Cream Topical 1.07 g/40mL Gel Topical 1.6 g/100mL Cream Topical 1.04 mg/55mL Cream Topical 1.6 g/100mL Cream Topical 0.968 g/40mL Solution Topical 0.3 g/30mL Cream Topical 1.296 g/120mL Cream Topical 1.2 g/120mL Cream Topical 0.76 g/40mL Cream Topical 0.375 g/25mL Stick Topical 20 mg/1g Cream Topical 5 g/100mL Cream Topical 0.77 g/55mL Cream Topical 9.75 g/150mL Cream Topical 1.35 g/30mL Liquid Topical 5.4 g/135mL Cream Topical 5.0 g/100mL Cream Topical 1.5 g/75mL Powder Topical 0.12 g/6g Powder Topical 0.06 g/6g Stick Topical 0.18 g/1.5g Cream Topical 1.2 g/60g Cream Topical 1.44 g/120g Cream Topical 2.56 g/160mL Cream Topical 13 mg/1mL Emulsion Oral 20 mg/0.3mL Cream Topical 1.6 mg/80mL Cream Topical 2 g/100mL Cream Topical 6.8 mg/80mL Cream Topical 0.3 g/20mL Cream Topical 1.575 g/35mL Cream Topical 1.5 g/150mL Cream Cutaneous 0.58 mL/45mL Cream Cutaneous 0.7 mL/35mL Cream Topical 6 % Cream Topical 60 mg/1g Cream Topical .01 g/100mL Cream Topical .012 g/100mL Lotion Topical 1.5 g/150mL Cream Topical 0.5 g/25mL Gel Topical 1.5 g/100mL Cream Topical 1.55 g/50mL Cream Topical 0.81 g/30mL Cream Topical 50 uL/1mL Cream Topical 17.5 uL/1mL Liquid Topical 17.5 uL/1mL Cream Topical 1.7 g/170.10g Cream Topical 0.044 g/4mL Cream Topical 0.77 g/70mL Cream Topical 1.5 mg/50mL Cream Topical 1.4 mg/140mL Cream Topical 7 mg/35mL Cream Topical 0.6 mg/30mL Tablet Oral Gel Topical 30 mg/1mL Cream Topical 0.45 mg/45mL Injectable foam Topical Cream Topical 0.6 g/60mL Cream Topical 2.10 g/60mL Emulsion Topical Spray Topical 20 g/100g Shampoo Topical 11.4 mg/380mL Solution Topical 15.2 mg/380mL Cream Topical 1 mg/50mL Lotion Topical 2 g/100g Cream Topical 5 g/100g Cream Topical 0.64 g/40mL Cream Topical 1.65 g/150mL Cream Topical 2 g/40mL Cream Topical 0.75 g/30mL Cream Topical 3.6 g/90mL Cream Topical 7 g/100mL Cream Topical 3.81 g/50mL Emulsion Topical 0.937 mg/50mL Ointment Topical 10 mg/1g Ointment Topical 20 mg/1g Lotion Topical 1 g/100mL Lotion Topical 15 mg/1mL Cream Topical 25 mg/1g Emulsion Topical 1.50 g/150mL Cream Topical 1.57 g/35mL Lipstick Topical 0.91 g/4.5g Liquid Topical 0.05 g/7g Liquid Topical 3.77 g/7g Kit Oral Cream Topical 0.32 g/30mL Cream Topical 1.12 g/50mL Cream Cutaneous 0.35 mL/35mL Liquid Topical 99.97 g/100mL Cream Cutaneous 0.3 g/30g Tablet, film coated Oral Paste Topical Solution Topical
- Not Available
Patent Number Pediatric Extension Approved Expires (estimated) Region US6103260 No 2000-08-15 2017-07-17
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
- Mass Spec (NIST)
- Not Available
- Not Available
Drug created on December 03, 2015 16:51 / Updated on May 10, 2021 04:40