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Displaying results 401 - 410 of 10000 in total
  1. Drug

    Phentermine

    go.drugbank.com/drugs/DB00191
    ApprovedIllicitInvestigational

    Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: Phentermine Resin ER
  2. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent

    International brands: Felodur ER, Plendil ERProducts: PLENDIL 2.5MG ER TABLET, PLENDIL 5 ER TABLETS (9MM)
  3. Drug

    Manidipine

    go.drugbank.com/drugs/DB09238
    ApprovedInvestigationalWithdrawn

    Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. … It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.

    Products: MANIDIPINA EG
  4. Drug

    Eribulin

    go.drugbank.com/drugs/DB08871
    ApprovedInvestigational

    Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439]. … Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic

    Products: ERIBULINA EG
  5. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    Tramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the … If used in higher doses, or with other opioids, there is a dose-related risk of overdose, respiratory depression, and death.

    Mixtures: TRAMADOLO E PARACETAMOLO EG, TRAMADOLO E PARACETAMOLO EGProducts: Ultram ER, Tramadol ER
  6. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam was given FDA approval on October 16, 1981.[L6148] … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.

    Synonyms: 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineProducts: Alprazolam ER, ALPRAZOLAM EG
  7. Drug

    Orphenadrine

    go.drugbank.com/drugs/DB01173
    ApprovedInvestigational

    A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

    Synonyms: N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine, N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamineProducts: Orphenadrine Citrate ER
  8. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

    Mixtures: HYDROCORTISONE 1% ET UREA 5% CREAM, Ti-U-lac LotionProducts: Rea Lo 39, Rea Lo 40
  9. Drug

    Gliclazide

    go.drugbank.com/drugs/DB01120
    ApprovedInvestigational

    [A39546] On the other hand, based on the pharmacological efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and a shorter half-life. … It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of

    Categories: Drugs Used in DiabetesProducts: GLICLAZIDE ZENTIVA LAB, GLICLAZIDE EG
  10. Drug

    Betiatide

    go.drugbank.com/drugs/DB14082
    Approved

    Products: Renoscint MAG3 1 mg Kit für ein radioaktives Arzneimittel