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Ranitidine
go.drugbank.com/drugs/DB00863ApprovedWithdrawn[L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine].
Categories: Heterocyclic Compounds, 1-RingProducts: ULCURAN 25 MG/ML 2 ML AMPUL, 10 ADET, RANOBEL 50 MG/2 ML ENJEKTABL AMPUL, 10 ADETGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[A233565] Glycopyrronium was originally granted FDA approval on 11 August 1961.[L33090] … [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, ULTIBRO BREEZHALER INHALATION POWDER HARD CAPSULE 110/50 MCGCategories: MATE 1 Substrates, Heterocyclic Compounds, 1-RingNebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigational[A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985] … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity.
Mixtures: AMLONEB 10 MG/10 MG TABLET, 30 ADET, AMLONEB 10 MG/10 MG TABLET, 90 ADETCategories: Heterocyclic Compounds, 2-Ring, Adrenergic beta-1 Receptor AgonistsApomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigational[A203597,A203618] Apomorphine was granted FDA approval on 20 April 2004.[L13919] … [A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diolAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approved[A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644] … Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.
Mixtures: AMOKLAVIN 875 MG/125 MG FILM KAPLI TABLET, 20 ADET, AUGMENTIN 500 MG/125 MG FILM KAPLI TABLET, 20 ADETCategories: Penicillin G, Heterocyclic Compounds, 1-RingGadopentetic acid
go.drugbank.com/drugs/DB00789ApprovedInvestigationalA complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Products: MAGNEVIST FLAKON, 20 ML, MAGNEVIST FLAKON, 10 MLLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … were found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40%.
Synonyms: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate, 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactoneProducts: MEVACOR 10 MG, LOVASTIN 20 MG TABLET, 15 ADETFinerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigational[A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449] … Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart
Categories: Heterocyclic Compounds, 2-RingProducts: KERENDİA 10 MG FİLM KAPLI TABLET, 28 ADET, KERENDİA 20 MG FİLM KAPLI TABLET, 28 ADETEnsulizole
go.drugbank.com/drugs/DB11115ApprovedEnsulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. … According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ranging between 74 and 148mM can be found in commercial sunscreen products [A27151].
Mixtures: Olay Professional ProX Age Repair SPF 30, Face It Radiance Makeup Base SPF 20 Pa++Categories: Heterocyclic Compounds, 2-RingKetoconazole
go.drugbank.com/drugs/DB01026ApprovedInvestigational[A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in 1981. … However, it was discovered that ketoconazole produces frequent gastrointestinal side effects and dose-related hepatitis.
Mixtures: CLINDAMICINA/KETOCONAZOL 100 MG/400MG, Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2%Categories: 14-alpha Demethylase Inhibitors