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Ethylhexyl methoxycrylene
go.drugbank.com/drugs/DB11226ApprovedIt is used as a solvent for crystalline UV filters and is easily emulsified and suitable for use in various lotions, creams, sprays, sticks, and gel formulations [F104].
Anthrax immune globulin human
go.drugbank.com/drugs/DB09057ApprovedInvestigationalThis binding of antibody to PA prevents PA-mediated cellular entry of toxic factors. … Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and
Ropeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models and clinical trials. … [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsSynonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L66...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: FENTANYL-PF 100 MCG/2 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, FENTANYL-PF 500 MCG/10 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 1 ADETEnfortumab vedotin
go.drugbank.com/drugs/DB13007ApprovedInvestigationaldevelopment of enfortumab vedotin was the result of a collaboration between Astellas Pharma and Seattle Genetics [A188868] and it was first approved for use in the United States in December 2019 under the brand
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAsciminib
go.drugbank.com/drugs/DB12597ApprovedInvestigationalAsciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). … [L39005] It has also shown benefit in Ph+ CML with the T315I mutation, which produces a mutant BCR-ABL1 which is typically treatment-resistant as compared to wild-type BCR-ABL1.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesFerumoxytol
go.drugbank.com/drugs/DB06215ApprovedInvestigational[L54506] It is comprised of superparamagnetic iron oxide nanoparticles which are coated by a semi-synthetic carbohydrate shell in an isotonic, neutral pH solution that may be administered at relatively
Cetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalCetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other sympt...
Mixtures: PAX MAX GEL®, NEXT GL GENOMMA LAB®Categories: P-glycoprotein inhibitors, P-glycoprotein substratesRaxibacumab
go.drugbank.com/drugs/DB08902ApprovedInvestigationalRaxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons.
Synonyms: PA mAbElectrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial
go.drugbank.com/bio_entities/BE0000235TargetHumansMitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:19641205, PubMed:2451557...
Synonyms: Aralar