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Dordaviprone
go.drugbank.com/drugs/DB14844ApprovedInvestigationalDordaviprone is a first-in-class small molecule imipridone. On August 6, 2025, dordaviprone was granted accelerated approval by the FDA.
Synonyms: 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one, 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin-5(1H)-oneRivanicline
go.drugbank.com/drugs/DB05855ExperimentalIt has subsequently been developed as a potential anti-inflammatory treatment for ulcerative colitis. … It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8.
ROX-888
go.drugbank.com/drugs/DB05364ExperimentalROX-888 is ROXRO's lead compound which is currently in Phase 3 trials for the treatment of acute pain, including post-operative pain.
FAV-201
go.drugbank.com/drugs/DB06130ExperimentalFAV-201 is a patient-specific immunotherapy for the treatment of T-cell lymphoma.
ALT-2074
go.drugbank.com/drugs/DB05631InvestigationalAn organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. … BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, primarily because of its ability to mimic the function of glutathione peroxidase.
Bromopride
go.drugbank.com/drugs/DB09018InvestigationalBromopride is a dopamine antagonist used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide. It is unavailable in America or the United Kingdom.
Categories: Drugs for Functional Gastrointestinal DisordersVanillyl butyl ether
go.drugbank.com/drugs/DB11299ApprovedIt is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent. … It is added to food products as a flavoring agent.
Pafuramidine
go.drugbank.com/drugs/DB06532InvestigationalPafuramidine, a prodrug of furamidine, currently has orphan status for _Pneumocystis jiroveci_ pneumonia.
Astodrimer
go.drugbank.com/drugs/DB11854InvestigationalIt is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
Categories: Compounds used in a research, industrial, or household setting