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Displaying results 4101 - 4110 of 10000 in total

Drug
Human Interleukin 8
go.drugbank.com/drugs/DB16456
Investigational
Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).
Categories: Interleukin-8, antagonists & inhibitorsSynonyms: INTERLEUKIN 8, Human Interleukin 8
Drug
P54
go.drugbank.com/drugs/DB05451
Experimental
It inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and iNOS.
Drug
XR5944
go.drugbank.com/drugs/DB06364
Experimental
XR5944 is a DNA bis-intercalating anticancer drug. It has both intercalating and antineoplastic activities.
Categories: Heterocyclic Compounds, 3-Ring
Drug
CYP-001
go.drugbank.com/drugs/DB15739
Investigational
CYP-001 is a mesenchymoangioblast (MCA)-derived mesenchymal stem cell (MSC) therapy that originates from the mesoderm. … When activated with fibroblast growth factor-2 (FGF-2), MCAs create colonies with specific phenotypes. These cells are then able to differentiate into bone, cartilage, and adipose tissue.
Drug
Edonerpic
go.drugbank.com/drugs/DB05938
Investigational
Edonerpic is a neurotrophic agent intended for the treatment of Alzheimer's disease which is under phase I clinical trial.
Categories: Heterocyclic Compounds, 1-Ring
Drug
FX06
go.drugbank.com/drugs/DB05685
Investigational
FX06 is a naturally occurring peptide derived from the neo-N-terminus of fibrin (Bbeta(15-42)). It prevents leukocyte migration through the gap junctions of endothelial cells. … It is being developed by Fibrex Medical Inc.
Drug
Ordopidine
go.drugbank.com/drugs/DB05196
Investigational
ACR325 is a dopaminergic stabiliser, which has demonstrated promising results in disease models for motor functions and psychoses. … ACR325 is developed for the treatment of Parkinson’s disease and psychoses, including bipolar disorder, for which disease existing therapies have only limited effect and considerable adverse side effects
Drug
Picrotoxin
go.drugbank.com/drugs/DB00466
Experimental
Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. [PubChem] … A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore.
Categories: GABA-A Receptor Antagonists, Compounds used in a research, industrial, or household setting
Drug
Biomed 101
go.drugbank.com/drugs/DB05851
Investigational
Biomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid. … Biomed 101 binds to the leukotriene B4 receptor, but does not affect interleukin-2 antitumor activity.
Drug
Tarenflurbil
go.drugbank.com/drugs/DB05289
Investigational
It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. … Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease.
Synonyms: (R)-flurbiprofen, (R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acid