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Tipifarnib
go.drugbank.com/drugs/DB04960InvestigationalIn June 2005, the FDA issued a Not Approvable Letter for Zarnestra. … Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer.
Benzimate
go.drugbank.com/drugs/DB05170ExperimentalIt is currently under investigation by AmpliMed and is in phase I of clinical trial. … The anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor & Gamble Company beginning in the 1990's.
Rupintrivir
go.drugbank.com/drugs/DB05102ExperimentalRupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused by rhinovirus. … Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections.
Inbakicept
go.drugbank.com/drugs/DB16479Investigational[L50592] This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without … It is one of the active ingredients in Anktiva, a combination product also containing [nogapendekin alfa], where a single inbakicept is complexed with two nogapendekin alfa components.
Synonyms: N-803 COMPONENT IL-15R.ALPHA.SU/FC FUSION PROTEINTyphoid Vaccine Live
go.drugbank.com/drugs/DB11050ApprovedInvestigationalThe vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by *Salmonella typhi* by inducing a local immune response in the intestinal tract.
AN-9
go.drugbank.com/drugs/DB05103InvestigationalPivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low toxicity and significant anticancer activity in vitro and in vivo. … greater potency than BA at inducing malignant cell differentiation and tumor growth inhibition and has demonstrated more favorable toxicological, pharmacological, and pharmaceutical properties than BA in
Synonyms: AN-9Trimethyltetradecylammonium
go.drugbank.com/drugs/DB17342ExperimentalSynonyms: 1-tetradecanaminium, n,n,n-trimethyl-Categories: Compounds used in a research, industrial, or household setting3,4-Dihydroxycinnamic Acid
go.drugbank.com/drugs/DB01880InvestigationalCategories: Compounds used in a research, industrial, or household settingAminoethyl nitrate
go.drugbank.com/drugs/DB13585ExperimentalCategories: Vasodilators Used in Cardiac DiseasesGlyceraldehyde-3-Phosphate Dehydrogenase
go.drugbank.com/drugs/DB17012ExperimentalCategories: Oxidoreductases Acting on Aldehyde or Oxo Group Donors