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Displaying results 4111 - 4120 of 10000 in total
  1. Drug

    Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15731
    Investigational

    Enrichment of CD362 expression in MSCs is being investigated for its role in immune modulation of injured tissue. … Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified on MSCs with enhanced clonogenicity and immunomodulatory properties.

  2. Drug

    Modipafant

    go.drugbank.com/drugs/DB16237
    Investigational

    Modipafant is under investigation in clinical trial NCT02569827 (Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore).

  3. Drug

    Lumefantrine co-artemether

    go.drugbank.com/drugs/DB13085
    ApprovedInvestigationalWithdrawn

    Unlike artemether, lumefantrine has a slower onset of action, resulting in clearance of residual parasites and a decrease in recrudescence rate. … Lumefantrine Co-Artemether (Riamet) has been investigated for the treatment of Malaria, Malaria, Falciparum, Malaria in Pregnancy, Uncomplicated Malaria, and Uncomplicated Knowlesi Malaria.

  4. Drug

    TMC-310911

    go.drugbank.com/drugs/DB15623
    Investigational

    [L12045] It is being investigated for use in HIV-1 infections. … [L12045,A191643] TMC-310911 is currently being investigated, in combination with other HIV therapies and antivirals, as a potential treatment for COVID-19 caused by SARS-CoV-2.[L12012]

    Categories: Antivirals for Systemic Use, Experimental Unapproved Treatments for COVID-19
  5. Drug

    Meglumine

    go.drugbank.com/drugs/DB09415
    ApprovedInvestigational

    Synonyms: N-methyl-D-glucamineCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Tanaproget

    go.drugbank.com/drugs/DB04787
    Experimental

    An analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging of the PR in positron emission tomography. … Because of this tanaproget may prove to produce fewer side effects in comparison. It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals.

  7. Drug

    Mavelertinib

    go.drugbank.com/drugs/DB16228
    Investigational

    Mavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).

  8. Drug

    Petrelintide

    go.drugbank.com/drugs/DB19442
    Investigational

    Petrelintide is under investigation in clinical trial NCT06662539 (Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities).

    Synonyms: 3,8-anhydro[N-(19-carboxynonadecanoyl)- L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L -lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-(2S)-α-2-aminoadipyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-arginyl, L-Prolinamide, N-(19-carboxy-1-oxononadecyl)-L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L-lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-5-carboxy-L-norvalyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-argi
  9. Drug

    Influenza A virus A/California/7/2009 (H1N1)-like hemagglutinin antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB14382
    Approved

    Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.

    Synonyms: Influenza A virus A/California/7/2009 (H1N1)-like hemagglutinin antigen (formaldehyde inactivated), Influenza a Virus A/california/7/2009(h1n1)-like Hemagglutinin Antigen (Formaldehyde Inactivated)
  10. Drug

    Influenza A virus A/Victoria/210/2009 X-187 (H3N2) hemagglutinin antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB14384
    ApprovedWithdrawn

    Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.

    Categories: Inactivated Influenza A Virus VaccineSynonyms: Influenza A virus A/Victoria/210/2009 X-187 (H3N2) hemagglutinin antigen (formaldehyde inactivated)