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Displaying results 4121 - 4130 of 10000 in total
  1. Drug

    Pregabalin

    go.drugbank.com/drugs/DB00230
    ApprovedInvestigational

    Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. … [A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent

    Mixtures: PREPLUS B12 75 MG/1 MG EFERVESAN TABLET, 14 ADET, PAGAMAX PLUS 150 MG/1 MG KAPSÜL ,60 KAPSÜLSynonyms: (S)-3-Isobutyl GABA, 3-Isobutyl GABA
  2. Target

    4-hydroxythreonine-4-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0001581
    TargetEscherichia coli (strain K12)

    Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP

    Polypeptides: 4-hydroxythreonine-4-phosphate dehydrogenaseSynonyms: 4-(phosphohydroxy)-L-threonine dehydrogenase
  3. Drug

    Thiocolchicoside

    go.drugbank.com/drugs/DB11582
    Investigational

    Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_. … It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663]

    Synonyms: Thiocolchicine 2-glucoside analogMixtures: DEKSİT 25 MG/4 MG TABLET, NAPROXENO 250 MG+TIOCOLCHICOSIDO 4 MG
  4. Drug

    Ezeprogind

    go.drugbank.com/drugs/DB16954
    Investigational

    Synonyms: N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1h-benzo(d)imidazol-2-amine, 1,4-piperazinedipropanamine, n'-1h-benzimidazol-2-yl-n,n-bis(2-methylpropyl)-
  5. Drug

    Melatonin

    go.drugbank.com/drugs/DB01065
    ApprovedInvestigationalNutraceuticalVet approved

    Reduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers. … Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958.

    Synonyms: 5-methoxy-N-acetyl tryptamine, N-[2-(5-methoxyindol-3-yl)ethyl]acetamideInternational brands: Mela-T
  6. Drug

    Pegvorhyaluronidase alfa

    go.drugbank.com/drugs/DB14912
    Investigational

    Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection

    Synonyms: ALFA, SUBSTITUTED ON N6 OF AN AVERAGE OF 4 TO, HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR-(36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM
  7. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine]. … Tramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the

    Mixtures: TRAMADOLO E PARACETAMOLO EG, TRAMADOLO E PARACETAMOLO EGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Indication

    Acute Hepatitis C Genotype 4

    go.drugbank.com/conditions/DBCOND0173312
    Drugs: Glecaprevir · Pibrentasvir
    Synonyms: Genotype 4 Acute Hepatitis C, Acute Hepatitis C Genotype 4
  9. Indication

    Bleeding caused by Hemophilia A

    go.drugbank.com/conditions/DBCOND0089512
    Drugs: Anti-inhibitor coagulant complex · Coagulation factor VIIa Recombinant Human · Emicizumab · Fitusiran · Moroctocog alfa · Rurioctocog alfa pegol +2 more
    Synonyms: Bleeding caused by Hemophilia A
  10. Indication

    Genotype 4 Chronic Hepatitis C

    go.drugbank.com/conditions/DBCOND0074476
    Drugs: Asunaprevir · Elbasvir · Glecaprevir · Grazoprevir · Ledipasvir · Pibrentasvir +3 more
    Synonyms: Chronic hepatitis C genotype 4, Hepatitis C virus genotype 4