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Nitrazepam
go.drugbank.com/drugs/DB01595ApprovedA benzodiazepine derivative used as an anticonvulsant and hypnotic.
Orciprenaline
go.drugbank.com/drugs/DB00816ApprovedA beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Categories: Adrenergics for Systemic UseMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.
Lecanemab
go.drugbank.com/drugs/DB14580ApprovedInvestigationalLecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology … [A253947,A253957] In clinical trials, it significantly reduced brain Aβ plaques compared to placebo.
Synonyms: Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimerOcriplasmin
go.drugbank.com/drugs/DB08888ApprovedWithdrawnOcriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012. … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system.
Dordaviprone
go.drugbank.com/drugs/DB14844ApprovedInvestigational[L53838] It is used to treat patients with diffuse midline glioma harboring an H3 K27M mutation. … Dordaviprone is a first-in-class small molecule imipridone. On August 6, 2025, dordaviprone was granted accelerated approval by the FDA.
Pemirolast
go.drugbank.com/drugs/DB00885ApprovedWithdrawnPemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. … As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis.
Nelarabine
go.drugbank.com/drugs/DB01280ApprovedInvestigationalNelarabine is an antineoplastic agent that is typically used to treat acute T-cell lymphoblastic leukemia, particularly T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL … [A2331] Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in the inhibition of DNA synthesis and cytotoxicity.
Ketoprofen
go.drugbank.com/drugs/DB01009ApprovedInvestigationalVet approvedKetoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Categories: Antiinflammatory Preparations, Non-Steroids for Topical UseProducts: PROFENID FEM (KETOPROFENO 50 MG) CAPSULASGarenoxacin
go.drugbank.com/drugs/DB06160ExperimentalGarenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use