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Displaying results 4141 - 4150 of 10000 in total
  1. Drug

    Bifikafusp alfa

    go.drugbank.com/drugs/DB19185
    Investigational

    Bifikafusp alfa is under investigation in clinical trial NCT05329792 (L19IL2/L19TNF in Skin Cancer Patients).

    Synonyms: Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human interleukin 2
  2. Drug

    4-methylumbelliferyl beta-D-glucoside

    go.drugbank.com/drugs/DB13177
    Experimental

    Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: 7-(beta-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one, 4-methylumbelliferyl β-D-glucoside
  3. Drug

    Metamizole

    go.drugbank.com/drugs/DB04817
    ApprovedInvestigationalWithdrawn

    Approvals of the NDA's for metamizole drug products were withdrawn on June 27, 1977 (see the Federal Register of June 17, 1977, 42 FR 30893). … Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability.

    Mixtures: HIOSCINA 20 MG + DIPIRONA 2.5 G, DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLECategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A Inducers
  4. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    A subdermal implant of levonorgestrel that slowly releases the hormone over a long-term period is also available. … [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD.

    Mixtures: CYBELLE 0.1 MG/0.02 MG FILM KAPLI TABLET, 21 ADET, LEVERETTE 0.15 MG/0.03 MG FILM KAPLI TABLET , 21 TABLETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Albuterol

    go.drugbank.com/drugs/DB01001
    ApprovedInvestigationalVet approved

    Salbutamol is formulated as a racemic mixture of the R- and S-isomers. … The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity.

    Mixtures: PRALAS 2,5 MG+0,5 MG/2,5 ML NEBÜLİZASYON ÇÖZELTİSİ, 20 ADET, İPRASAL 0,5 MG+2,5 MG/2,5 ML NEBULİZASYON İÇİN TEK DOZLUK İNHALASYON ÇÖZELTİSİ İÇEREN FLAKON, 20 ADETCategories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic Agonists
  6. Drug

    Acapatamab

    go.drugbank.com/drugs/DB18838
    Investigational

    Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).

    Synonyms: (scfv)2-scfc, bispecific, Mmunoglobulin scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain
  7. Drug

    Lorundrostat

    go.drugbank.com/drugs/DB18957
    Investigational

    Lorundrostat is under investigation in clinical trial NCT06153693 (Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension).

    Synonyms: N-(trans-4-acetamidocyclohexyl)-2-{4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]piperazin-1-yl}acetamide, 1-Piperazineacetamide, N-[trans-4-(acetylamino)cyclohexyl]-4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]-
  8. Drug

    Stachyose

    go.drugbank.com/drugs/DB19276
    Experimental

    Synonyms: Gal(.alpha.1->6)gal(.alpha.1->6)glc(.alpha.1->2.beta.)fru, -d-glucopyranoside, .beta.-d-fructofuranosyl o-.alpha.-d-galactopyranosyl-(1->6)-o-.alpha.-d-galactopyranosyl-(1->6)-
  9. Drug

    Black widow spider antivenin (equine)

    go.drugbank.com/drugs/DB14113
    Approved

    Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.[L12792]

    Synonyms: LATRODECTUS IMMUNE F(AB)2
  10. Drug

    Benzatropine

    go.drugbank.com/drugs/DB00245
    ApprovedInvestigational

    It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. … potency for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether, 3α-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane