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Displaying results 4151 - 4160 of 10000 in total
  1. Drug

    Wheat germ oil

    go.drugbank.com/drugs/DB16570
    Investigational

    Mixtures: WHEATGERM OIL + E
  2. Drug

    Catridecacog

    go.drugbank.com/drugs/DB09310
    Approved

    Coagulation Factor XIII A-Subunit (Recombinant) is available in the US as the commmercially available product Tretten, and in the EU as NovoThirteen. … When activated by thrombin at the site of injury, the FXIII A2B2 pro-enzyme is cleaved resulting in activation of the catalytic A-subunit and dissociation from its carrier B-subunit.

    Synonyms: Factor XIII A-Subunit (Recombinant), Coagulation Factor XIII A-Subunit (recombinant)
  3. Drug

    Pipotiazine

    go.drugbank.com/drugs/DB01621
    ApprovedInvestigationalWithdrawn

    However, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: NEUROVAN®, PIPORTIL ® L-4SOLUCION INYECTABLE AL 2.5% (100 MG).
  4. Drug

    Triacetin

    go.drugbank.com/drugs/DB16005
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Ellagic acid

    go.drugbank.com/drugs/DB08846
    Investigational

    of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar lentigines. … In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables.

    Categories: Cytochrome P-450 CYP2E1 Inhibitors, Heterocyclic Compounds, 1-Ring
  6. Drug

    Sodium borate

    go.drugbank.com/drugs/DB14505
    Approved

    Mixtures: Sel De Perou
  7. Drug

    Estradiol acetate

    go.drugbank.com/drugs/DB13952
    ApprovedVet approved

    Because of the difference in potency between estradiol and estrone, menopause (and a change in primary hormone from estradiol to estrone) is associated with a number of symptoms associated with this reduction … in potency and in estrogenic effects.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: Estradiol 3-acetate, Estradiol-3-acetate
  8. Drug

    Grapiprant

    go.drugbank.com/drugs/DB12836
    InvestigationalVet approved

    [A39838] This type of molecules is currently in development for veterinary patients.[A39816] This class of drugs was defined in 2013 by the World Health Organization. … [L4766] Grapiprant has been approved in March 2016 by the FDA's Center for Veterinary Medicine as a non-cyclooxygenase inhibiting NSAID for veterinary use.[A39836]

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  9. Drug

    Asimadoline

    go.drugbank.com/drugs/DB05104
    Investigational

    It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases. … Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Bavituximab

    go.drugbank.com/drugs/DB05136
    Investigational

    Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections. … It binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4.