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Propyphenazone
go.drugbank.com/drugs/DB13524InvestigationalPropyphenazone is a non-steroidal anti-inflammatory agent with analgesic effects.[A275063, A275068]
Synonyms: 4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one, 1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-oneMixtures: ALJIL 150 MG/300 MG/50 MG TABLET, 20 ADET, MINOSET PLUS 250 MG/150 MG/50 MG TABLET, 20 ADETDienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalIt is a derivative of 19-nortestosterone and has antiandrogenic properties. … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.
Synonyms: 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile, 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-oneMixtures: Foxinette 0,03 mg/2 mg 21+7 - Filmtabletten, Sibilla 0,03 mg/2 mg 21 FilmtablettenRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets … Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain.
International brands: Risperidal M-TabCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigationalIt is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine]. … into active metabolites: (+)-tramadol and its primary metabolite (+)-O-desmethyl-tramadol (M1) are agonists of the μ opioid receptor while (+)-tramadol inhibits serotonin reuptake and (-)-tramadol inhibits
Mixtures: DOR-2®, Skudexa 75 mg/25 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDexmedetomidine
go.drugbank.com/drugs/DB00633ApprovedInvestigationalVet approvedAn agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Synonyms: (+)-4-((S)-α,2,3-trimethylbenzyl)imidazole, (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazoleCategories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistDOTA-Arg-Pro-Lys-Pro-Gln-Gln-Phe-2Thi-Gly-Leu-Met(O2)-NH2 Actinium AC-225
go.drugbank.com/drugs/DB18208ExperimentalSynonyms: -2-amino-4-(methylsulfonyl)-, (2S)-, [225Ac]Butanamide, N2-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-3-(2-thienyl)-L-alanylglycyl-L-leucylVirulizin
go.drugbank.com/drugs/DB17098InvestigationalSynonyms: Virulizin-2.gamma., Bos taurus bile extract (heat hydrolyzed; mw < 3000)Reveglucosidase alfa
go.drugbank.com/drugs/DB17665InvestigationalSynonyms: Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase (acid maltase, aglucosidase alfa) produced in chinese hamster ovary (cho) cells3-(alpha-D-galactopyranosyloxy)-N-(3-{4-[3-({2-[(3-{4-[3-({[3-(hexopyranosyloxy)-5-nitrophenyl]carbonyl}amino)propyl]piperazin-1-yl}propyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)propyl]piperazin-1-yl}propyl)-5-nitrobenzamide
go.drugbank.com/drugs/DB04210ExperimentalSynonyms: 3-(alpha-D-galactopyranosyloxy)-N-(3-{4-[3-({2-[(3-{4-[3-({[3-(hexopyranosyloxy)-5-nitrophenyl]carbonyl}amino)propyl]piperazin-1-yl}propyl)amino]-3,4-dioxocyclobut-1-en-1-yl}amino)propyl]piperazin-1-yl, }propyl)-5-nitrobenzamideGonyautoxin II
go.drugbank.com/drugs/DB19186InvestigationalGonyautoxin II is under investigation in clinical trial NCT04799041 (Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study).
Synonyms: Gonyautoxin 2, 1h,10h-pyrrolo(1,2-c)purine-9,10,10-triol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, 9-(hydrogen sulfate), (3as-(3a.alpha.,4.alpha.,9.beta.,10ar*))- 11.alpha.Categories: Heterocyclic Compounds, 2-Ring