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Displaying results 4171 - 4180 of 10000 in total
  1. Drug

    Retlirafusp alfa

    go.drugbank.com/drugs/DB17517
    Investigational

    Synonyms: Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion, protein with peptide linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor (human isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal
  2. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    [A178816] Bupropion is sometimes used as an add-on agent to first-line treatments of depression such as selective serotonin reuptake inhibitor (SSRI) medications when there is a treatment-failure or … While it has comparable effectiveness to typical first-line options for the treatment of depression such as SSRIs,[A178798,A178804] bupropion is a unique option for the treatment of MDD as it lacks any

    Mixtures: Appbutamone-DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  3. Target

    VLA-4 (very late antigen-4)

    go.drugbank.com/bio_entities/BE0010014
    TargetHumans

    Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. … Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin.

    Polypeptides: Integrin alpha-4Synonyms: VLA-4 subunit alpha, VLA-4 subunit beta
  4. Drug

    Ketoprofen

    go.drugbank.com/drugs/DB01009
    ApprovedInvestigationalVet approved

    Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

    Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: m-Benzoylhydratropic acid, 2-(3-Benzoylphenyl)propionic acid
  5. Drug

    Cyanocobalamin

    go.drugbank.com/drugs/DB00115
    ApprovedInvestigationalNutraceutical

    Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. … This drug was initially approved by the FDA in 1942 [FDA label].

    Mixtures: Tonicol Et A-D-C Ampoules/comprimes, Mvc 9+4 InjCategories: Heterocyclic Compounds with 4 or More Rings, Vitamin B Complex
  6. Drug

    Ampicillin

    go.drugbank.com/drugs/DB00415
    ApprovedInvestigationalVet approved

    Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

    Synonyms: D-(−)-6-(α-aminophenylacetamido)penicillanic acid, D-(−)-ampicillinMixtures: AUROPENNZ 1.5 G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE, AMPICILLINA E SULBACTAM IBI
  7. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    Potassium is an essential nutrient, like [Calcium] and [Magnesium]. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. … Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for rehydration, nutrition, and replenishment of electrolytes.

    Mixtures: New Chapter's D'adamo 4 Your Type Multiple for Type O, One A Day TabSynonyms: K
  8. Drug

    Naloxone

    go.drugbank.com/drugs/DB01183
    ApprovedInvestigationalVet approved

    [L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.

    Mixtures: Bupensan Duo 4 mg/1 mg-Sublingualtabletten, TILIDIN 50/4 RETARD 1A PHACategories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein substrates
  9. Drug

    Megestrol acetate

    go.drugbank.com/drugs/DB00351
    ApprovedInvestigationalVet approved

    As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer. … 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: MGA, 17α-Acetoxy-6-dehydro-6-methylprogesterone
  10. Drug

    Hepatitis B immune globulin

    go.drugbank.com/drugs/DB05276
    ApprovedInvestigational

    Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. … Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B.

    Categories: hepatitis B immunoglobulinSynonyms: Hepatitis B immune globulin, Hepatitis B immune globulin human