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MDX-214
go.drugbank.com/drugs/DB06110ExperimentalIt is developed for the treatment of EGF-R overexpressing cancers.
ALGRX 1207
go.drugbank.com/drugs/DB06482ExperimentalIt was being developed by Anesiva, but trials have halted.
Dexloxiglumide
go.drugbank.com/drugs/DB04856InvestigationalAs the D-isomer of loxiglumide, it retains all pharmacological properties of loxiglumide but is more potent.
Lubazodone
go.drugbank.com/drugs/DB09196ExperimentalIt acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist.
Olenasufligene relduparvovec
go.drugbank.com/drugs/DB16264InvestigationalIt is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]
VTX-801
go.drugbank.com/drugs/DB17646InvestigationalIt is being investigated in Wilson Disease.[L45924]
RP-A501
go.drugbank.com/drugs/DB17647InvestigationalIt is being investigated for Danon disease.[L45934]
EGT-301
go.drugbank.com/drugs/DB17649ExperimentalIt consists of an adeno-associated viral vector serotype 9 (AAV9) containing the human Iduronate-2-sulfatase (I2S) transgene designed to restore I2S functional deficiency in patients with Hunter syndrome
DTX-101
go.drugbank.com/drugs/DB17699InvestigationalIt was previously investigated for the treatment of hemophilia B; however, the clinical development of DTX-101 was discontinued.[L46103]
Coagulin-B
go.drugbank.com/drugs/DB17703Experimental[A259038, A259043] It was previously investigated for the treatment of hemophilia; however, the manufacturing company discontinued the Phase I trial in 2004, halting its further development and investigation