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Displaying results 411 - 420 of 10000 in total
  1. Drug

    Baclofen

    go.drugbank.com/drugs/DB00181
    ApprovedInvestigational

    Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.

    Mixtures: Innoprax-5Categories: GABA-B Receptor Agonists
  2. Drug

    Tobramycin

    go.drugbank.com/drugs/DB00684
    ApprovedInvestigational

    such as β-lactams and cephalosporins. … [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to

    Mixtures: TOBRAMICINA E DESAMETASONE EG, TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADETCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  3. Drug

    Pheniramine

    go.drugbank.com/drugs/DB01620
    Approved

    Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine]. … Pheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as [cetirizine] and [loratadine].

    Mixtures: ANTIBEKSIN SURUP, 100 ML, OCTILIA ALLERGIA E INFIAMMAZIONECategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Aminophylline

    go.drugbank.com/drugs/DB01223
    ApprovedInvestigational

    Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: AMINOFILINA 250 MG / 10 ML SOLUCION INYECTABLE, AMINOCARDOL 10 ML 240 MG 100 AMPUL
  5. Drug

    Hydroxyethyl Starch

    go.drugbank.com/drugs/DB09106
    ApprovedInvestigational

    HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose. … Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.

    Mixtures: PF POLIHES (HES 200/0,5) %6 IV INFZÜYON IÇIN ÇÖZELTI, 500 ML SETLI, PF POLIHES (HES 200/0,5) %6 IV INFZÜYON IÇIN ÇÖZELTI, 500 ML SETSIZCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Roflumilast

    go.drugbank.com/drugs/DB01656
    ApprovedInvestigational

    Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. … The cream formulation was first approved by the FDA in July 2022 [L42580] and by Health Canada in April 2023.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ROFLUNG 0,5 MG SAŞE ,30 SAŞE, ROFLUNG 0,5 MG SAŞE ,90 SAŞE
  7. Drug

    Armodafinil

    go.drugbank.com/drugs/DB06413
    ApprovedInvestigational

    Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. … (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2B6 InducersSynonyms: (–)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide, R-modafinil
  8. Drug

    Glatiramer

    go.drugbank.com/drugs/DB05259
    ApprovedInvestigational

    encephalitis (MS animal model). … [A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate is a first-line drug for patients with MS.

    Synonyms: (T,G)-A-L, COP 1Products: GLATIR® 40 MG/ML, โคแพคซอน (20 MG/ML)
  9. Drug

    Lapatinib

    go.drugbank.com/drugs/DB01259
    ApprovedInvestigational

    Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. … Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSynonyms: N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine
  10. Indication

    Uncontrolled with <1.8 mg daily liraglutide

    go.drugbank.com/conditions/DBCOND0106443
    Drugs: Insulin degludec
    Synonyms: Uncontrolled with <1.8 mg daily liraglutide