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Lidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedEver since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. … It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding
Mixtures: Bus and Classroom Yellow, Care Bus and Classroom YellowCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Anesthetics for Topical UseDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
go.drugbank.com/bio_entities/BE0001300TargetHumansMay act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K
Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositideMagnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalIt can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). … Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Mixtures: UFOR, UFORCategories: Drugs for Acid Related DisordersMineral oil
go.drugbank.com/drugs/DB11057ApprovedInvestigationalVet approvedIt is also used as a mild laxative for human or veterinary uses. … Unrefined or mildly treated mineral oils are classified as Group 3 carcinogens by the World Health Organizations, as chronic exposure to these aromatics including alkylated polycyclic aromatic compounds
Categories: Drugs for ConstipationProducts: Enema Mineral Oil Ready To Use, Leader enema mineral oil ready to useFibrinogen human
go.drugbank.com/drugs/DB09222ApprovedInvestigationalIt is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin. … It works by replacing a specific protein in the blood, fibrinogen (factor I), that helps with blood clotting.
Mixtures: ARTISS SOLUTIONS FOR SEALANT, DEEP FROZEN, Artiss Solutions for Sealant, Deep FrozenProducts: HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL, Fibryga 1g Powder and Solvent for Solution for Injection or InfusionBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigationalBudesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.
Mixtures: SYMBICORT RAPIHALER SUSPENSION FOR INHALATION 80/4.5 mcg/actuation, SYMBICORT RAPIHALER SUSPENSION FOR INHALATION 160/4.5 mcg/actuationCategories: Agents to Treat Airway Disease, Corticosteroids for Systemic UseRomosozumab
go.drugbank.com/drugs/DB11866ApprovedInvestigationalIn a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months … to other osteoperosis therapies[L9554].
Categories: Drugs for Treatment of Bone DiseasesProducts: EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML, EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17MLLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … ] and, in doing so, prevents the formation of the 70S initiation complex which is essential for bacterial reproduction.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Antibacterials for Systemic UseProducts: ZYVOX SOLUTION FOR INFUSION 2 mg/ml, Prezolid 2mg/ml Solution for InfusionRurioctocog alfa pegol
go.drugbank.com/drugs/DB16007ApprovedInvestigationalFactor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous … [A245139] Rurioctocog alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and prevent bleeding episodes.
Products: ADYNOVATE 1500IU Powder and Solvent for Solution for Injection, ADYNOVATE 2000IU Powder and Solvent for Solution for InjectionAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalfor whom oral treatment is either contraindicated or ineffective. … This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth.
International brands: Alprox-TDProducts: CAVERJECT POWDER FOR INJECTION 10 mcg/ml, CAVERJECT POWDER FOR INJECTION 20 mcg/ml