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Displaying results 411 - 420 of 5504 in total
  1. Drug

    Sorafenib

    go.drugbank.com/drugs/DB00398
    ApprovedInvestigational

    It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis.

    Products: NEXAVAR ® 200MG, SORAFENIB EG
  2. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative

    Products: UMETREX Pemetrexed Injection 10mg/ml Solution for Infusion, PEMETREXED EG
  3. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and thiazolidinediones. … It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release.

    Products: REPAGLINIDE EG, Gluconorm 1.0mg
  4. Drug

    Ketoconazole

    go.drugbank.com/drugs/DB01026
    ApprovedInvestigational

    [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole] and [clotrimazole], due to its broad spectrum and good absorption. … However, it was discovered that ketoconazole produces frequent gastrointestinal side effects and dose-related hepatitis.

    Products: YUCOMY CREAM 20MG/G, NIZORAL SUSPENSION 20MG/ML
  5. Drug

    Cabozantinib

    go.drugbank.com/drugs/DB08875
    ApprovedInvestigational

    It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer.

    Products: CABOMETYX FILM COATED TABLET 20MG, CABOMETYX 20mg film-coated tablets
  6. Drug

    Melperone

    go.drugbank.com/drugs/DB09224
    Investigational

    It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the elderly) and schizophrenia as It is known to be well-tolerated with an excellent safety profile. … Recently, it has been studied as a treatment of psychosis related to Parkinson's disease [L1316].

    Products: MELPERON ARISTO 10MG, MELPERON - CT 50MG FILMTAB
  7. Drug

    Calcium carbonate

    go.drugbank.com/drugs/DB06724
    ApprovedInvestigational

    It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin.

    Mixtures: Coral Calcium Plus Vitamin D 210mg/100iu, Antacid and Anti-Gas ChewProducts: Antacid Fruit Chew, Antacid Soft Chew
  8. Drug

    Mivacurium

    go.drugbank.com/drugs/DB01226
    ApprovedWithdrawn

    It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.

    Products: MIVACRON 2MG/ML INJ. 10ML AMPOULE
  9. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    [T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain.

    Mixtures: Vicodin ES, Vicodin ESProducts: Robidone Syr 1mg/ml, Robidone 1mg/ml Syr
  10. Drug

    Moclobemide

    go.drugbank.com/drugs/DB01171
    ApprovedInvestigational

    A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficaci...

    Products: Manerix Tab 100mg, MOCLOBEMID AL 150MG