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Displaying results 411 - 420 of 10000 in total
  1. Drug

    6-bromoindirubin-3'-oxime

    go.drugbank.com/drugs/DB03444
    Experimental

    Synonyms: 6-BIO, 6-bromoindirubin-3'-oximeCategories: Heterocyclic Compounds, 2-Ring, Glycogen Synthase Kinase 3, antagonists & inhibitors
  2. Drug

    6-Hydroxymethyl-7,8-Dihydropterin

    go.drugbank.com/drugs/DB02119
    Experimental

    Synonyms: 6-Hydroxymethyl-7,8-DihydropterinCategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Lomitapide

    go.drugbank.com/drugs/DB08827
    Approved

    [A7367] Lomitapide was first approved by the FDA in December 2012 and the EMA in July 2013 as an adjunct to a low-fat diet and other lipid-lowering treatments.[A275444, A275446] … Lomitapide, marketed under the brand names Juxtapid (USA) and Lojuxta (EU), is a first-in-class, small-molecule inhibitor of microsomal triglyceride transfer protein (MTP).

    Synonyms: 9H-FLUORENE-9-CARBOXAMIDE, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-2-YL)CARBONYL)AMINO)-1-PIPERIDINYL)BUTYL)-, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)BIPHENYL-2-YL)CARBONYL)AMINO)PIPERIDIN-1-YL)BUTYL)-9H-FLUORENE-9-CARBOXAMIDECategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A Inhibitors
  4. Drug

    2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid

    go.drugbank.com/drugs/DB07914
    Experimental

    Metabolic product of biphenyl; from Pseudomonas putida.

    Synonyms: 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid
  5. Drug

    Sulfachlorpyridazine

    go.drugbank.com/drugs/DB11461
    ExperimentalVet approved

    A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

    Synonyms: 4-Amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide, 4-amino-N-(6-chloropyridazin-3-yl)benzenesulfonamideMixtures: TP-KSM 125/625 mg/g Water Soluble Powder
  6. Drug

    Ezogabine

    go.drugbank.com/drugs/DB04953
    ApprovedWithdrawn

    It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures … Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine.

    Synonyms: ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate, N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester
  7. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.

    Synonyms: 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acidMixtures: ALERMED® D, FEXU D® SUSPENSION
  8. Drug

    Estazolam

    go.drugbank.com/drugs/DB01215
    ApprovedIllicitInvestigational

    A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.

    Synonyms: 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  9. Drug

    Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (propiolactone inactivated)

    go.drugbank.com/drugs/DB16918
    ApprovedWithdrawn

    A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde.

    Synonyms: Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (propiolactone inactivated)Categories: Inactivated Influenza A Virus Vaccine
  10. Drug

    Aminobenzoic acid

    go.drugbank.com/drugs/DB02362
    ApprovedWithdrawn

    A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.

    Synonyms: 1-Amino-4-carboxybenzene, 4-aminobenzoateMixtures: Multi B Complex Plus 500mg Vitamin C Tablets, VIVA B COMPLEX TABLET