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Displaying results 411 - 420 of 5498 in total
  1. Drug

    Sorafenib

    go.drugbank.com/drugs/DB00398
    ApprovedInvestigational

    It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis.

    Products: NEXAVAR ® 200MG, SORAFENIB EG
  2. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    [T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain.

    Mixtures: Vicodin ES, Vicodin ESProducts: Robidone Syr 1mg/ml, Robidone 1mg/ml Syr
  3. Drug

    Duloxetine

    go.drugbank.com/drugs/DB00476
    ApprovedInvestigational

    [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence.

    Products: DULOXETINA EG, YENTREVE 20MG
  4. Drug

    Cabozantinib

    go.drugbank.com/drugs/DB08875
    ApprovedInvestigational

    It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer.

    Products: CABOMETYX FILM COATED TABLET 20MG, CABOMETYX 20mg film-coated tablets
  5. Drug

    Melperone

    go.drugbank.com/drugs/DB09224
    Investigational

    It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the elderly) and schizophrenia as It is known to be well-tolerated with an excellent safety profile. … Recently, it has been studied as a treatment of psychosis related to Parkinson's disease [L1316].

    Products: MELPERON ARISTO 10MG, MELPERON - CT 50MG FILMTAB
  6. Drug

    Mivacurium

    go.drugbank.com/drugs/DB01226
    ApprovedWithdrawn

    It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.

    Products: MIVACRON 2MG/ML INJ. 10ML AMPOULE
  7. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.

    Products: Fenivir - Fieberblasencreme 10mg/g Creme, EX-LOVIR % 1 KREM 2 G
  8. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and thiazolidinediones. … It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release.

    Products: REPAGLINIDE EG, Gluconorm 1.0mg
  9. Drug

    Ketoconazole

    go.drugbank.com/drugs/DB01026
    ApprovedInvestigational

    [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole] and [clotrimazole], due to its broad spectrum and good absorption. … However, it was discovered that ketoconazole produces frequent gastrointestinal side effects and dose-related hepatitis.

    Products: YUCOMY CREAM 20MG/G, NIZORAL SUSPENSION 20MG/ML
  10. Drug

    Macitentan

    go.drugbank.com/drugs/DB08932
    ApprovedInvestigational

    [L39105] It was subsequently approved by the FDA in March 2024.[L50622] … [L35890] It was first approved by the FDA in 2013. Macitentan differs from its predecessor [bosentan] in part due to its lower risk of hepatotoxicity.

    Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASProducts: OPSUMIT 10MG, OPSUMIT FILM-COATED TABLET 10MG