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NCX 1015
go.drugbank.com/drugs/DB05825ExperimentalNCX 1015 is nitric oxide-releasing derivative of prednisolone developed for the treatment of inflammatory bowel disease (IBD) by NicOx SA.
Betaprodine
go.drugbank.com/drugs/DB01473ExperimentalIllicitIt has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)
Maropitant
go.drugbank.com/drugs/DB11427ExperimentalVet approvedIt was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
VPM4001
go.drugbank.com/drugs/DB05089ExperimentalIt consists of irradiated human LNCaP cells that have been genetically modified to permanently secrete interferon-γ and interleukin-2 (LNCaP/IL-2/IFN-γ).
CYT-6091
go.drugbank.com/drugs/DB05991ExperimentalIt was under investagtion in clinical trials NCT00356980 and NCT00436410 for the treatment of various cancers.
TB-402
go.drugbank.com/drugs/DB06050InvestigationalIt is expected to be developed as a potential treatment to prevent blood clot formation in connection with certain types of heart arrhythmia, such as atrial fibrillation.
Bisegliptin
go.drugbank.com/drugs/DB06127InvestigationalIt is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion
HNM01
go.drugbank.com/drugs/DB06531ExperimentalIt entered Phase 1 clinical trials for the treatment of HIV infections but was discontinued during this phase
2-Methoxyestradiol
go.drugbank.com/drugs/DB02342InvestigationalIt has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.