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AP5280
go.drugbank.com/drugs/DB05112ExperimentalAP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic designed to increase the therapeutic index relative to conventional, small-molecule platinum agents.
NGX267
go.drugbank.com/drugs/DB05152InvestigationalIt is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
CPD 923
go.drugbank.com/drugs/DB05856ExperimentalIt shows efficacy in vivo studies, as well as a favourable pre-clinical tolerability profile.
Talopram
go.drugbank.com/drugs/DB09190ExperimentalIt was researched in the 1960s and 1970s but never marketed.
Demegestone
go.drugbank.com/drugs/DB13857ExperimentalIt was previously marketed in France as Lutionex, but has since been discontinued.
Cholesteryl chloride
go.drugbank.com/drugs/DB14045ExperimentalIt is presented as a liquid crystal that forms clockwise liquid crystals.
MEDI6012
go.drugbank.com/drugs/DB14833InvestigationalRecombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction
MRK-003
go.drugbank.com/drugs/DB17015ExperimentalIt is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]
Synonyms: (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxideICG-136
go.drugbank.com/drugs/DB17343ExperimentalICG-136 is a compound chimeric antigen receptor (cCAR) T-cell therapy developed by iCell Gene Therapeutics. It was investigated for the treatment of acute myeloid leukemia.
Synonyms: CD123-CD33cCAR T-cells, ICG136:CD123-CD33cCAR T-cellsLuLym-T
go.drugbank.com/drugs/DB17405ExperimentalLuLym-T is an investigational autologous immune cell therapy consisting of activated T Lymphocytes. Developed by Lukas Biomedical, Inc., it is currently being investigated in hepatocellular carcinoma.
Synonyms: LuLym-T, Autologous Activated T Lymphocytes (ATL)