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Denifanstat
go.drugbank.com/drugs/DB17576InvestigationalDue to its antineoplastic activities, it is being investigated for various cancers.
AC3056
go.drugbank.com/drugs/DB05230ExperimentalAC3056 is a non-peptide antioxidant that acts as an inhibitor of vascular cell adhesion molecule expression originally developed by Aventis Pharmaceuticals. It as since been acquired by Amylin Pharmaceuticals and has completed phase I tr...
Mexazolam
go.drugbank.com/drugs/DB15489Investigational[A184910] Mexazolam's structure is similar to that of other benzodiazepines such as [oxazolam] and [cloxazolam].
3-(5-Amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid
go.drugbank.com/drugs/DB08668ExperimentalThis compound belongs to the aminobenzoic acid derivatives. … These are benzoic acids (or derivatives thereof) containing an amine group attached to the benzene moiety. 3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid targets the protein methionine aminopeptidase
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide
go.drugbank.com/drugs/DB03456ExperimentalIt is known to target cathepsin K. … This compound belongs to the n-acyl-alpha amino acids and derivatives.
SYNB1353
go.drugbank.com/drugs/DB17666InvestigationalIt is designed to consume methionine in the gastrointestinal tract to prevent its absorption and conversion into homocysteine.[L45983]
Enrofloxacin
go.drugbank.com/drugs/DB11404InvestigationalVet approvedDue to the identification of fluoroquinolone-resistant strains of _Campylobacter_, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat flocks of poultry.
Fenbendazole
go.drugbank.com/drugs/DB11410InvestigationalVet approvedFenbendazole is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs, cats, rabbits and seals.
KIN-3248
go.drugbank.com/drugs/DB17587InvestigationalIt was designed to mainly target FGFR2 and FGFR3 alterations, which act as oncogenic drivers in 10-20% of cholangiocarcinoma and 20-35% of urothelial cancers, respectively. … [L45469] In February 2023, Kinnate Biopharma received Fast Track designation from the FDA for KIN-3248 to treat unresectable, locally advanced or metastatic cholangiocarcinoma (CCA).[L45474]
Olesoxime
go.drugbank.com/drugs/DB05185InvestigationalFor example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]
Synonyms: 4-Cholesten-3-one, oxime, cholest-4-en-3-one, oxime