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Displaying results 1 - 10 of 5894 in total
  1. Drug

    Doxylamine

    go.drugbank.com/drugs/DB00366
    ApprovedInvestigationalVet approved

    Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.

    Mixtures: Care One Cold Mutli SymptomProducts: Unisom SleepTabs, Unisom-2 Tablets
  2. Drug

    Valerian

    go.drugbank.com/drugs/DB13196
    Approved

    Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. … Valerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance.

    Mixtures: Bio-strath No. 8 GouttesProducts: Unisom Natural Source
  3. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    As histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect behaviour including dopamine, norepinephrine, serotonin, acetylcholine, and opioid [A1539].

    Mixtures: Unisom PM Pain Nighttime Sleep Aid and Pain Reliever, Cough Syr W Codeine Diphenhyd HCl & Ammon ClCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  4. Drug

    Glucosamine

    go.drugbank.com/drugs/DB01296
    Approved

    [A232289] Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. … Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and findings with unclear clinical significance

    Products: UNISON GLUCOSAMINE 500MG TABLET, UNISON GLUCOSAMINE 500MG EFFERVESCENT TABLETS
  5. Drug

    Alfacalcidol

    go.drugbank.com/drugs/DB01436
    ApprovedInvestigationalNutraceutical

    In Canada, it is marketed as ONE-ALPHA, which manages hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in adults with chronic renal failure. … Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones.

    International brands: One AlphaProducts: One-alpha, BON-ONE
  6. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy. … [L7823] In addition to the above uses, levonorgestrel is used as a component of long-term combination contraceptives.

    Synonyms: 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one, 17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-oneMixtures: Amethia Lo, Amethia Lo
  7. Drug

    Xylometazoline

    go.drugbank.com/drugs/DB06694
    Approved

    Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. … [A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies.

    Products: Otrivin 0,1 % - Nasenspray ohne Konservierungsmittel, Otrivin 0,05 % - Nasenspray ohne Konservierungsmittel
  8. Drug

    Juniperus monosperma pollen

    go.drugbank.com/drugs/DB10727
    Approved

    Juniperus monosperma pollen is the pollen of the Juniperus monosperma plant. Juniperus monosperma pollen is mainly used in allergenic testing.

    Products: One Seed Juniper, One Seed Juniper Pollen
  9. Drug

    Benzoic acid

    go.drugbank.com/drugs/DB03793
    ApprovedInvestigational

    This leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. … As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids.

    Mixtures: PAK HUP KO OINTMENTProducts: S Panax All In One Mist, Seo Jeong Ho Hwang Chill Mist
  10. Drug

    Guselkumab

    go.drugbank.com/drugs/DB11834
    ApprovedInvestigational

    IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation [A20357]. … Developed by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the market name Tremfya for the treatment of adult patients with moderate-to-severe plaque psoriasis.

    Products: Tremfya One-press, Tremfya One-Press 100mg/ml Solution for Injection