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Displaying results 4231 - 4240 of 10000 in total
  1. Drug

    Sabestomig

    go.drugbank.com/drugs/DB19326
    Investigational

    Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).

    Synonyms: Immunoglobulin G1-kappa/lambda, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279) and HAVCR2 (hepatitis A virus cellular receptor 2, T cell immunoglobulin and mucin domains family member, 3, TIM3, TIM-3, TIMD3, CD366)], humanized and Ho
  2. Drug

    Ersodetug

    go.drugbank.com/drugs/DB18182
    Investigational

    Synonyms: (119-216), hinge 1-12 (217-228), CH2 M45.1 (279) (2, gamma2 heavy chain Homo sapiens (1-444) [VH(Homo sapiens IGHV3-20*01 (98.0%) -(IGHD)-IGHJ6*01 (93.8%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG2*02 (100%), G2m23 CH2 M45.1 (CH1
  3. Drug

    Vinblastine

    go.drugbank.com/drugs/DB00570
    ApprovedInvestigational

    (Merck, 11th ed.)

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: VINBLASTINE RICHTER 5 MG FLAKON, VINBLASTINA10 MG X 1 FCO.
  4. Drug

    Mannitol

    go.drugbank.com/drugs/DB00742
    ApprovedInvestigational

    Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. … As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced.

    Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol A
  5. Drug

    Cofirasersen

    go.drugbank.com/drugs/DB19037
    Investigational

    Cofirasersen is under investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary

    Synonyms: Dna, d(p-thio)((2'-o,4'-c-((s)-ethylidene))m5rc-(2'-o,4'-c-((s)-ethylidene))m5rc-(2'-o,4'-c-((s)-ethylidene))m5rc-g-a-t-a-g-m5c-t-g-g-t-(2'-o,4'-c-((s)-ethylidene))m5ru-(2'-o,4'-c-((s)-ethylidene))rg-(, -L-MANNOFURANO)M5C-(3'->4')-(2',5'-ANHYDRO-6'-DEOXY-4'-C-(HYDROXYMETHYL)-.ALPHA.-L-MANNOFURANO)M5C-G-A-T-A-
  6. Drug

    Lerodalcibep

    go.drugbank.com/drugs/DB19071
    ApprovedInvestigational

    Lerodalcibep is a recombinant fusion protein that binds to and inhibits proprotein convertase subtilisin kexin type 9 (PCSK9). … [L54738] Approved by the FDA on December 15, 2025, lerodalcibep is indicated as an adjunct to diet and exercise to reduce low-density lipoprotein cholesterol (LDL-C) in adults with hypercholesterolemia

    Categories: Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsSynonyms: Engineered binding protein (1-96) anti-(human proprotein convertase subtilisin/kexin type 9), derived from human tenth fibronectin type iii domain, fused via peptidyl linker (97gsgsgs102) to human serum, Protein lib003 (recombinant human proprotein convertase subtilisin/kexin type 9 ligand-binding tenth fibronectin type iii domain) fusion protein with peptide (synthetic 6-amino acid linker) fusion protein
  7. Drug

    Muparfostat

    go.drugbank.com/drugs/DB05808
    Investigational

    Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic

    Synonyms: -D-MANNAN, (1->3)-, 6-(DIHYDROGEN PHOSPHATE) TRIS(HYDROGEN SULFATE)
  8. Drug

    XPro1595

    go.drugbank.com/drugs/DB16454
    Investigational

    XPro1595 is an investigational dominant-negative protein that neutralizes soluble TNF.

    Categories: Experimental Unapproved Treatments for COVID-19Synonyms: HOMOSAPIENS TUMOR NECROSIS FACTOR,SOLUBLE FORM (V1>M, R31>C, C69>V, Y87>H, C101>A, A145>R), MONOMER, PEGYLATED ON CYSTEINE 31 : S-((3RS)-(2-((3-(.OMEGA., -METHOXYPOLY(OXYETHANE-1,2-DIYL))PROPYL)CARBAMOYL)ETHYL)-2,5-DIOXOPYRROLIDIN-3-YL)-L-CYSTEINYL
  9. Drug

    GSK-269962A

    go.drugbank.com/drugs/DB17030
    Experimental

    GSK-269962A is a Rho kinase (ROCK) inhibitor with both ROCK1 and ROCK2 affinity.[A253012]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzamide, n-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)-4-(2-(4-morpholinyl)ethoxy)-, N-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)-4-(2-(4-morpholinyl)ethoxy)benzamide
  10. Drug

    Rasburicase

    go.drugbank.com/drugs/DB00049
    ApprovedInvestigational

    Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified <i>Saccharomyces cerevisiae</i> strain. … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_.

    Products: FASTURTEC 1,5 MG/1 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET, FASTURTEC 7,5 MG/5 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1ADET