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Fimasartan
go.drugbank.com/drugs/DB09279InvestigationalFimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. … It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials.
Categories: Agents Acting on the Renin-Angiotensin SystemLIC-477
go.drugbank.com/drugs/DB05363ExperimentalLIC-477is indicated to be suitable for the treatment of psychosomatic disturbances, epilepsy, trigeminal neuralgia and cerebral spasticity.
Antroquinonol
go.drugbank.com/drugs/DB12326InvestigationalAntroquinonol has been used in trials studying the treatment of Hyperlipidemias, Non-small Cell Lung Cancer, and Non-small Cell Lung Cancer Stage IV.
JB991
go.drugbank.com/drugs/DB05081ExperimentalIn addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug will be applied topically on the skin. … The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro.
ACA 125
go.drugbank.com/drugs/DB05489InvestigationalAntiidiotypic antibodies bearing the internal image of an antigen expressed on the surface of the tumor are suited to this approach. … An IgG1 murine monoclonal anti-idiotype antibody (Ab2), ACA-125, was developed to bind to anti-CA 125 antibodies.
Guanadrel
go.drugbank.com/drugs/DB00226ApprovedGuanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Cinitapride
go.drugbank.com/drugs/DB08810InvestigationalIt is marketed in Spain and Mexico.
Synonyms: 4-Amino-N-(1-(3-cyclohexen-1-ylmethyl)-4-piperidyl)-2-ethoxy-5-nitrobenzamidePentetreotide
go.drugbank.com/drugs/DB12602ApprovedWithdrawnPentetreotide has been used in trials studying the diagnosis of Cushing's syndrome.
Categories: Compounds used in a research, industrial, or household settingIroxanadine
go.drugbank.com/drugs/DB05444ExperimentalIt induces phosphorylation of p38 SAPK, which plays an important role in EC homeostasis. endothelial cell (EC). … EC function plays a central role in vascular diseases (e.g. atherosclerosis, restenosis, diabetic angiopathies, microvascular angina, peripheral arterial disease).
Procarbazine
go.drugbank.com/drugs/DB01168ApprovedInvestigationalAn antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Synonyms: N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine, 4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide