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5-Methoxy-N,N-diisopropyltryptamine
go.drugbank.com/drugs/DB01441ExperimentalIllicitSince 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. This substance is abused for its hallucinogenic effects. … 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine,
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 5-methoxy-N,N-bis(1-methylethyl)-1H-indole-3-ethanamine, N-(1-methylethyl)-N-{2-[5-(methyloxy)-1H-indol-3-yl]ethyl}propan-2-amineArecoline
go.drugbank.com/drugs/DB04365ExperimentalIt is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands. … An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors.
Categories: Heterocyclic Compounds, 1-RingFimasartan
go.drugbank.com/drugs/DB09279InvestigationalIt has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. … Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure.
Categories: Heterocyclic Compounds, 1-Ring, Angiotensin Receptor AntagonistsSynonyms: BR1015-1, BR1015-35-methoxy-N,N-dimethyltryptamine
go.drugbank.com/drugs/DB14010IllicitInvestigationalThis drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South America in religious and spiritual rituals. … 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties.
Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor AgonistsSynonyms: 3-[2-(N,N-Dimethylamino)ethyl]-5-methoxy-indole, 5-methoxy-N,N-dimethyl-1H-indole-3-ethanamineBardoxolone
go.drugbank.com/drugs/DB12651InvestigationalBardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. … It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are under high levels of intrinsic
anti-alpha5Beta1-integrin antibody
go.drugbank.com/drugs/DB05870ExperimentalThe integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial
Dirucotide
go.drugbank.com/drugs/DB04921InvestigationalDirucotide is a synthetically prepared peptide. In particular, the sequence prepared is a 17 amino acid chain that is identical to a section of myelin basic protein (MBP) that is found in humans. … Dirucotide has been developed for the treatment of multiple sclerosis (MS). Developed at the University of Alberta, dirucotide is being investigated by BioMS Medical Corp.
Progabide
go.drugbank.com/drugs/DB00837ExperimentalIn clinical trials, progabide has been investigated for Parkinson's disease, schizophrenia, clinical depression and anxiety disorder; its therapeutic effectiveness in these conditions is not fully elucidated
Amuvatinib
go.drugbank.com/drugs/DB12742InvestigationalAmuvatinib has been used in trials studying the treatment of Solid Tumors and Small Cell Lung Carcinoma. … Amuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-d)pyrimidin-4-yl-, 4-[1]Benzofuro[3,2-D]Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-CarbothioamideZeteletinib
go.drugbank.com/drugs/DB21491InvestigationalZeteletinib is under investigation in clinical trial NCT03780517 (Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors). … Zeteletinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Zeteletinib is a tyrosine kinase inhibitor.