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HNM01
go.drugbank.com/drugs/DB06531ExperimentalIt entered Phase 1 clinical trials for the treatment of HIV infections but was discontinued during this phase
Lucanthone
go.drugbank.com/drugs/DB04967InvestigationalOne of the schistosomicides, it has been replaced largely by hycanthone and more recently praziquantel. (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.
Acebutolol
go.drugbank.com/drugs/DB01193ApprovedInvestigationalA cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Categories: Antihypertensive Agents Indicated for HypertensionST-36
go.drugbank.com/drugs/DB17275ExperimentalIn 2017, it received orphan drug designation by the FDA for the treatment of glioma.[L47341]
Phelimin
go.drugbank.com/drugs/DB18332Experimental[L48151] It is under investigation for the treatment of hyperphenylalaninemia.
NKG2D-ACE2 CAR-NK Cell
go.drugbank.com/drugs/DB15727InvestigationalThe GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity. … The transmembrane NKG2D and intracellular 2B4 domains are required for optimal NK signalling and subsequent cell-mediated cytotoxicity.
Vicriviroc
go.drugbank.com/drugs/DB06652InvestigationalVicriviroc, also known as SCH 417690 and SCH-D, is currently in clinical trials for the management of HIV-1.
Carumonam
go.drugbank.com/drugs/DB13553ExperimentalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseBrodimoprim
go.drugbank.com/drugs/DB13795ExperimentalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use