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Tioguanine
go.drugbank.com/drugs/DB00352ApprovedInvestigationalThe drug is used in the therapy of acute leukemia.
Synonyms: 6-TG, TGCategories: Heterocyclic Compounds, 2-RingPerospirone
go.drugbank.com/drugs/DB08922InvestigationalIt is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502]. … It is commonly present as the hydrated hydrochloride salt form.
Synonyms: SM-9018, cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximideCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingHydroxocobalamin
go.drugbank.com/drugs/DB00200ApprovedInvestigationalHydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Synonyms: Vitamin B-12bMixtures: TRIBEDOCE C/L, ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5)Xamoterol
go.drugbank.com/drugs/DB13781ApprovedXamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. … It modulates the sympathetic control of the heart but has no agonist action on β2-adrenoceptors.
Categories: Adrenergic beta-1 Receptor Agonists, Heterocyclic Compounds, 1-RingZolasartan
go.drugbank.com/drugs/DB20140ExperimentalZolasartan is a small molecule drug. The usage of the INN stem '-sartan' in the name indicates that Zolasartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic). … Zolasartan has a monoisotopic molecular weight of 554.05 Da.
Categories: Agents Acting on the Renin-Angiotensin System, Heterocyclic Compounds, 1-RingSantonin
go.drugbank.com/drugs/DB19377ApprovedWithdrawnSantonin is a anthelmintic drug that was previously approved in the US to treat certain parasitic infections.
Dexamethasone acetate
go.drugbank.com/drugs/DB14649ApprovedInvestigationalVet approvedCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. … [L10701] Recently, dexamethasone has been a drug of interest in the treatment of COVID-19.
Mixtures: BAYCUTEN® N CREMA, BAYCUTEN® N CREMACategories: P-glycoprotein inducers, P-glycoprotein inhibitorsClonixin
go.drugbank.com/drugs/DB09218InvestigationalClonixin is a non-steroidal anti-inflammatory drug.
Mixtures: LIDERIUM-TR, DOBRIX ®Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigational[A189717] Tafamidis is structurally similar to diflusinal.[A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid, 6-BENZOXAZOLECARBOXYLIC ACID, 2-(3,5-DICHLOROPHENYL)-Prednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approvedPrednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Synonyms: Predniso(lo)ne, delta(1)-HydrocortisoneInternational brands: Decortin H, Di-Adreson F